Strain Data Sheet



BRC No.RBRC10463
TypeTargeted MutationCartagena
SpeciesMus musculus
Strain nameB6-Itgb3bp<tm1.1tfw>/Yuwa
Former Common nameCenpR KO B6
H-2 Haplotype
ES Cell line
Background strain
Strain developmentDeveloped by Tatsuo Fukagawa, Osaka University, and deposited by Yuichi Wakabayashi, Chiba Cancer Center, in 2018. ES cells derived from C57BL/6J were used. C57BL/6J genetic background. Crossing to a Rosa-cre line, a DNA fragment flanked by loxP was removed. Y choromosome is from C57BL/6J.
Strain descriptionItgb3bp (integrin beta 3 binding protein (beta3-endonexin), CenpR) knockout mice. Homozygous mutants are grossly normal. Exon 4 of the Itgb3bp was deleted.
Colony maintenance
ReferencesCancer Sci., 108(11):2142-2148 (2017). 28795467

Health Report

Examination Date / Room / Rack


Gene info
Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter
Itgb3bpintegrin beta 3 binding protein (beta3-endonexin)4Itgb3bp<tm1.1tfw>targeted mutation 1.1, Tatsuo Fukagawa

Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter
loxPphage P1 loxP4loxP


Donor DNAPhage P1 loxP site, mouse Itgb3bp genomic DNA
Research applicationCre/loxP system
Specific Term and ConditionsPrior to requesting the BIOLOGICAL RESOURCE, the RECIPIENT must obtain approval from the DEPOSITOR using the Approval Form.
DepositorYuichi Wakabayashi (Chiba Cancer Center)
Strain Statusan icon for Frozen spermFrozen sperm
Strain AvailabilityRecovered litters from cryopreserved sperm (2 to 4 months)
Cryopreserved sperm (within 1 month)
Additional Info.Necessary documents for ordering:
  1. Approval form (Japanese / English)
  2. Order form (Japanese / English)
  3. Category I MTA: MTA for distribution with RIKEN BRC (Japanese / English)
  4. Acceptance of responsibility for living modified organism (Japanese / English)

BRC mice in Publications

No Data