Strain Data Sheet

RBRC10458

Strain Information

Image
BRC No.RBRC10458
TypeCRISPR/Cas9Cartagena
SpeciesMus musculus molossinus
Strain nameMSM-Cdkn2a<em1Arak>/Yuwa
Former Common namep16KOMSM-19
H-2 Haplotype
ES Cell line
Background strainMSM/Ms
Appearance
Strain developmentDeposited by Yuichi Wakabayashi, Chiba Cancer Center, in 2018. Developed by Kimi Araki, Kumamoto University using ES cells derived from MSM. CRISPR/Cas9 deleted exon 1 of the p16 (Cdkn2a).
Strain descriptionp16 (Cdkn2a) knockout mice on MSM genetic background.
Colony maintenance
References
Identification of Stmm3 locus conferring resistance to late-stage chemically induced skin papillomas on mouse chromosome 4 by congenic mapping and allele-specific alteration analysis.
Saito M, Okumura K, Miura I, Wakana S, Kominami R, Wakabayashi Y
Exp. Anim., 63(3):339-48 (2014). 25077764

Health Report

Examination Date / Room / Rack

Gene

Gene SymbolGene NameChr.Allele SymbolAllele NameCommon NamesPromoterDiseases Related to This Gene
Cdkn2acyclin dependent kinase inhibitor 2A4Cdkn2aendonuclease-mediated mutation 1, Kimi Araki

Phenotype

Annotation by Mammalian phenotyhpe ontology
  • no abnormal phenotype detected(MP:0002169)
    • Detailed phenotype data

    Ordering Information

    Donor DNA
    Research applicationCancer Research
    Specific Term and ConditionsPrior to requesting the BIOLOGICAL RESOURCE, the RECIPIENT must obtain approval from the DEPOSITOR using the Approval Form.
    DepositorYuichi Wakabayashi (Chiba Cancer Center)
    Strain Statusan icon for Frozen spermFrozen sperm
    Strain AvailabilityRecovered litters from cryopreserved sperm (2 to 4 months)
    Additional Info.Necessary documents for ordering:
    1. Approval form (Japanese / English)
    2. Order form (Japanese / English)
    3. Category I MTA: CRISPR/Cas9 genome edited bioresources (Japanese / English)
    4. Acceptance of responsibility for living modified organism (Japanese / English)

    Genotyping protocol -PCR-

    BRC mice in Publications

    No Data