Strain Data Sheet



BRC No.RBRC10458
SpeciesMus musculus molossinus
Strain nameMSM-Cdkn2a<em1Arak>/Yuwa
Former Common namep16KOMSM-19
H-2 Haplotype
ES Cell line
Background strainMSM/Ms
Strain developmentDeposited by Yuichi Wakabayashi, Chiba Cancer Center, in 2018. Developed by Kimi Araki, Kumamoto University using ES cells derived from MSM. CRISPR/Cas9 deleted exon 1 of the p16 (Cdkn2a).
Strain descriptionp16 (Cdkn2a) knockout mice on MSM genetic background.
Colony maintenance
ReferencesExp. Anim., 63(3):339-48 (2014). 25077764

Health Report

Examination Date / Room / Rack


Gene info
Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter
Cdkn2acyclin dependent kinase inhibitor 2A4Cdkn2a<em1Arak>endonuclease-mediated mutation 1, Kimi ArakiArf, ARF-INK4a, INK4a-ARF, MTS1, p16, p16INK4a, p19ARF, Pctr1


Donor DNA
Research applicationCancer Research
Specific Term and ConditionsPrior to requesting the BIOLOGICAL RESOURCE, the RECIPIENT must obtain approval from the DEPOSITOR using the Approval Form.
DepositorYuichi Wakabayashi (Chiba Cancer Center)
Strain Statusan icon for Frozen spermFrozen sperm
Strain AvailabilityRecovered litters from cryopreserved sperm (2 to 4 months)
Additional Info.Necessary documents for ordering:
  1. Approval form (Japanese / English)
  2. Order form (Japanese / English)
  3. Category I MTA: CRISPR/Cas9 genome edited bioresources (Japanese / English)
  4. Acceptance of responsibility for living modified organism (Japanese / English)

Genotyping protocol -PCR-

BRC mice in Publications

No Data