Strain Data Sheet

RBRC10450

Strain Information

Image
BRC No.RBRC10450
TypeCRISPR/Cas9Cartagena
SpeciesMus musculus
Strain nameB6-Tecrl<em1Akih>
Former Common nameTecrl KO
H-2 Haplotype
ES Cell line
Background strain
Appearance
Strain developmentDeveloped by Yusuke Ohno and Akio Kihara, Hokkaido University in 2016. This strain was generated in the C57BL/6 background with the CRISPR/Cas9.
Strain descriptionTecrl (trans-2,3-enoyl-CoA reductase-like) mutant mice. 1bp insertion at Exon 1. Homozygous mutants are grossly normal.Tecrl<em1Akih>:GCAGCAGTTCTCAATAGTGTTATATATAGAAATCAGATCGGTCATTGTTTCCCAGCCTGCTAAATAAAACTAGACCGCTGGAATGGCATGCCACTTGACCTCCAGGGCGTCCACAGCAGTGTTTAACAGGCACAAAGGGAGTACTCTTGCAAGTATCTCCTGTTTACATGCCAGATTCCCCTGCTAGTTCACACAATGTTCAAAAGGCACAAGTCCCTGGAACGCAAGAGGGAATTGTTATTCCAGGGACTGCCACAGTCCACAATGAAGAATAATGCGAGAAATTTCCACTCTTTGTCACAACTTGTACTCTCAGCAGGCCCGCTCAAAA(A)CTACTACAGCAGTCAAACATTCAAAAACGACTCACTTTGAGATCGAAATACTGGATGCTCATACAAGAAAACAAATATGTATTGTGGATAAG
Colony maintenance
References

Health Report

Examination Date / Room / Rack

Gene

Gene SymbolGene NameChr.Allele SymbolAllele NameCommon NamesPromoterDiseases Related to This Gene
Tecrltrans-2,3-enoyl-CoA reductase-like5Tecrlendonuclease-mediated mutation 1, Akio Kihara
  • catecholaminergic polymorphic ventricular tachycardia 3(MedGEN)
  • Phenotype

    Annotation by Mammalian phenotyhpe ontology
  • no abnormal phenotype detected(MP:0002169)
  • Detailed phenotype data

    Ordering Information

    Donor DNA
    Research application
    Specific Term and ConditionsIn publishing the research results to be obtained by use of the BIOLOGICAL RESOURCE, an acknowledgment to the DEPOSITOR is requested.
    DepositorAkio Kihara (Hokkaido University)
    Strain Statusan icon for Frozen spermFrozen sperm
    Strain AvailabilityRecovered litters from cryopreserved sperm (2 to 4 months)
    Cryopreserved sperm (within 1 month)
    Additional Info.Necessary documents for ordering:
    1. Order form (Japanese / English)
    2. Category I MTA: CRISPR/Cas9 genome edited bioresources (Japanese / English)
    3. Acceptance of responsibility for living modified organism (Japanese / English)

    Genotyping protocol -PCR-

    BRC mice in Publications

    No Data