Information1 | |
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Image | |
BRC No. | RBRC10360 |
Type | Targeted Mutation![]() |
Species | Mus musculus |
Strain name | C57BL/6-Il22ra2<tm1.1Ksat> |
Former Common name | Il22ra2-/- mice |
H-2 Haplotype | |
ES Cell line | |
Background strain | C57BL/6JJcl |
Appearance | |
Strain development | Developed by Katsuaki Sato, Miyazaki University in 2018. JN/2 ES cells derived from B6 were used, and then mice were backcrossed to C57BL/6J over 12 generations. C57BL/6 congenic strain. Stop cassette was knocked in at Exon 1 of the Il22ra2 gene. |
Strain description | Il22ra2(interleukin 22 receptor, alpha 2) knockout mice. |
Colony maintenance | |
References | Front. Immunol., 9, 1418 (2018). 29977242 |
Health Report | |
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Examination Date / Room / Rack |
Gene | |
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Gene info | Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter EGFPEnhanced Green Fluorescent Protein (Aequorea victoria)10EGFP Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter HBEGFheparin-binding EGF-like growth factor (human)10HBEGF Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter loxPphage P1 loxP10loxP Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter herpes simplex virus thymidine kinase (HSV TK) polyA10 |
Information2 | |
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Donor DNA | STOP cassette (human HBEGF cDNA, jellyfish EGFP cDNA, herpes simplex virus thymidine kinase (HSV TK) poly A), Phage P1 loxP site, mouse Il22ra2 genomic DNA |
Research application | Cre/loxP system Fluorescent Proteins/lacZ System |
Specific Term and Conditions | In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested. Front Immunol. 2018 Jun 21, 9:1418. doi, 10.3389/fimmu.2018.01418Prior to requesting the BIOLOGICAL RESOURCE, the RECIPIENT must obtain approval from the DEVELOPER (Dr. Katsuaki Sato) using the Approval Form. The Recipient acknowledges that RIKEN (and/or its original provider) reserves title to the Material. The Recipient will not transfer the Material to any scientists. The Recipient will not publish or present Research result without obtaining prior permission from the DEVELOPER (Dr. Katsuaki Sato). The Recipient will send Dr. Katsuaki Sato any abstract of submission, oral or written presentation, and/or copy of draft of paper or research article which is resulted from the Research at least 30 days prior to the submission. The RECIPIENT agrees to use this BIOLOGICAL RESOURCE as a collaboration with the DEVELOPER (Dr. Katsuaki Sato). |
Depositor | Katsuaki Sato (RIKEN) |
Strain Status | ![]() ![]() |
Strain Availability | Recovered litters from cryopreserved sperm (2 to 4 months) Cryopreserved sperm (within 1 month) |
Additional Info. | Necessary documents for ordering:
Genotyping protocol -PCR- |
BRC mice in Publications |
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No Data |