Strain Data Sheet



BRC No.RBRC10315
SpeciesMus musculus
Strain nameB6.B6D2-Bdh1<em1Fkao>
Former Common name
H-2 Haplotype
ES Cell line
Background strainC57BL/6JJmsSlc
Strain developmentDeveloped by Masatake Osawa in 2016 and deposited by Toshiyuki FUkao, Gifu University. This strain was generated by the Genome editing using fertilized eggs derived from B6D2, and then backcrossed to C57BL/6J for 5 generations.
Strain descriptionBdh1 (3-hydroxybutyrate dehydrogenase, type 1) mutant mice. 1 and 6 bp deletion at exon containing translation initiation codon. Bdh1<em1Fkao>: 1 and 6 bp deletionsCATGAGGGTGTACCTCGAGctgggcctagttggttaacttgaataacttgaagaagaaaatggctgttcttgactaaaactcccaagtggaaggcgctgagcatgcgttttgtgtttcagagccaccagaaggaagcagagcgtcttacaacttggtgccacgatgctagctgcccgtctctccagacccctgtcacagctcccaggaaaagccctaagtgtccgtgacagagaaaatgggacaaggtaagcaaccaaagggagggttggccttgaagaccaccctaaacatcttcactacctgccagacctcagtgctcaggagacaggacttcccgtggCTCACGGGGCAAATAGGAGT
Colony maintenance
ReferencesJ. Inherit. Metab. Dis., 43, 960-968 (2020). 32279332

Health Report

Examination Date / Room / Rack


Gene info
Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter
Bdh13-hydroxybutyrate dehydrogenase, type 116Bdh1<em1Fkao>endonuclease-mediated mutation 1, Toshiyuki Fukao


Donor DNA
Research application
Specific Term and ConditionsPrior to requesting the BIOLOGICAL RESOURCE, the RECIPIENT must obtain approval from the DEPOSITOR using the Approval Form. In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested. J. Inherit. Metab. Dis. 43, 960-968 (2020), doi:10.1002/jimd.12243
DepositorToshiyuki Fukao (Gifu University)
Strain Statusan icon for Frozen spermFrozen sperm
Strain AvailabilityRecovered litters from cryopreserved sperm (2 to 4 months)
Cryopreserved sperm (within 1 month)
Additional Info.Necessary documents for ordering:
  1. Approval form (Japanese / English)
  2. Order form (Japanese / English)
  3. Category I MTA: CRISPR/Cas9 genome edited bioresources (Japanese / English)
  4. Acceptance of responsibility for living modified organism (Japanese / English)

BRC mice in Publications

No Data