Strain Information | |
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Image | |
BRC No. | RBRC10306 |
Type | Targeted Mutation![]() |
Species | Mus musculus |
Strain name | C57BL/6-Foxc2<tm1.1Motoj> |
Former Common name | floxed Foxc2 |
H-2 Haplotype | |
ES Cell line | |
Background strain | C57BL/6JJcl |
Appearance | |
Strain development | Developed by Masaru Motojima, Tokai University in 2015. MK6 ES cells derived from C57BL/6J were used. C57BL/6J background. |
Strain description | Foxc2(forkhead box C2) floxed mouse. |
Colony maintenance | |
References | Conditional knockout of Foxc2 gene in kidney: efficient generation of conditional alleles of single-exon gene by double-selection system. Motojima M, Ogiwara S, Matsusaka T, Kim S Y, Sagawa N, Abe K, Ohtsuka M Mamm. Genome, 27 (1-2), 62-69 (2016). 26542959 |
Health Report | |
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Examination Date / Room / Rack | 2024/11/05Room:2-検Rack:C 2024/08/05Room:2-検Rack:C |
Gene | |||||||
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Gene Symbol | Gene Name | Chr. | Allele Symbol | Allele Name | Common Names | Promoter | Diseases Related to This Gene |
Foxc2 MGI:1347481 | forkhead box C2 | 8 | Foxc2<tm1.1Motoj> | targeted mutation 1.1, Masaru Motojima | |||
Frt | yeast FRT (flippase recombination target) site | 8 | Frt | ||||
Frt | yeast FRT (flippase recombination target) site | 8 | Frt | ||||
loxP | phage P1 loxP | 8 | loxP | ||||
loxP | phage P1 loxP | 8 | loxP | ||||
loxP | phage P1 loxP | 8 | loxP | ||||
neo | neomycin resistance gene (E. coli) | 8 | mouse Phosphoglycerate kinase promoter (PGK promoter), phage T7 gb2 promoter | ||||
rox | Bacteriophage D6 rox site | 8 | rox |
Phenotype | |
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Annotation by Mammalian phenotyhpe ontology | |
Detailed phenotype data |
Ordering Information | |
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Donor DNA | Phage P1 loxP sites, Phage D6 Rox site, yeast FRT (flipase recombination target) sites, mouse Phosphoglycerate kinase promoter (PGK promoter), phage T7 gb2 promoter(synthetic), E. coli Neomycin resistance gene, mouse Foxc2 genomic DNA |
Research application | Cre/loxP system Developmental Biology Research FLP/frt system Hematological Research |
Specific Term and Conditions | In publishing the research results to be obtained by use of the BIOLOGICAL RESOURCE, an acknowledgment to the DEPOSITOR is requested. |
Depositor | Masaru Motojima (Tokai University) |
Strain Status | ![]() ![]() ![]() |
Strain Availability | Recovered litters from cryopreserved embryos (2 to 4 months) Cryopreserved sperm (within 1 month) |
Additional Info. | Necessary documents for ordering:
Genotyping protocol -PCR- |
BRC mice in Publications |
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No Data |