RBRC10291

Information1

Image
BRC No.RBRC10291
TypeTargeted MutationCartagena
SpeciesMus musculus
Strain nameB6.Cg-Itpr2<tm1Kmik> Itpr3<tm1Kmik>
Former Common nameIP3R2 IP3R3 double knockout mice
H-2 Haplotype
ES Cell lineJ1 [129S4/SvJae]
Background strain
Appearance
Strain development
Strain description
Colony maintenance
ReferencesScience, 309(5744) 2232-2234 (2005). 16195467
J. Clin. Invest., 124(11) 4773-4780 (2014). 25329695
Eur. J. Neurosci., 27(10) 2665-2675 (2008). 18547250

Health Report

Examination Date / Room / RackNo Data

Gene

Gene info
Gene symbolGene nameChr.Allele symbolAllele namePromoter
Itpr3inositol 1,4,5-triphosphate receptor 317Itpr3<tm1Kmik>targeted mutation 1, Katsuhiko Mikoshiba

Gene symbolGene nameChr.Allele symbolAllele namePromoter
neoneomycin resistance gene17mouse phosphoglycerate kinase promoter (PGK promoter)

Gene symbolGene nameChr.Allele symbolAllele namePromoter
Itpr2inositol 1,4,5-triphosphate receptor 26Itpr2<tm1Kmik>targeted mutation 1, Katsuhiko Mikoshiba

Gene symbolGene nameChr.Allele symbolAllele namePromoter
lacZbeta-galactosidase (E. coli)6

Gene symbolGene nameChr.Allele symbolAllele namePromoter
neoneomycin resistance gene6mouse phosphoglycerate kinase promoter (PGK promoter)

Gene symbolGene nameChr.Allele symbolAllele namePromoter
nlsSV40 large T antigen nuclear localization signal (NLS)6nls

Information2

Donor DNAMouse Itpr2(deleted), Itpr3(deleted), Mouse PGK promoter, Escherichia coli neomycin-resistant gene, Escherichia coli lacZ gene, SV40 large tumor nuclear location signal , Mouse PGK pA
Research applicationFluorescent Proteins/lacZ System
Specific Term and ConditionsThe RECIPIENT of BIOLOGICAL RESOURCE must use it as a collaborative study with DEPOSITOR. The RECIPIENT of BIOLOGICAL RESOURCE must obtain a prior written consent on use of it from the DEPOSITOR. The RECIPIENT must contact the DEPOSITOR in the case of application for any patents or commercial use based on the results from the use of the BIOLOGICAL RESOURCE.
DepositorKatsuhiko Mikoshiba (RIKEN)
Strain Statusan icon for Frozen embryosFrozen embryos
Strain AvailabilityRecovery and QC required prior to distribution
Additional Info.

BRC mice in Publications

No Data