Strain Information | |
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Image | |
BRC No. | RBRC10254 |
Type | Targeted Mutation![]() |
Species | Mus musculus |
Strain name | C57BL/6-Il17rb<tm1Tgi> |
Former Common name | IL17RB KO |
H-2 Haplotype | |
ES Cell line | |
Background strain | |
Appearance | |
Strain development | Developed by Masaru Taniguchi, RIKEN Center for Integrative Medical Sciences in 2012. B6JN/1 ES cells were used. C57BL/6 genetic background. |
Strain description | Il17rb (interleukin 17 receptor B) knockout mice. |
Colony maintenance | |
References | Development and function of invariant natural killer T cells producing T(h)2- and T(h)17-cytokines. Watarai H, Sekine-Kondo E, Shigeura T, Motomura Y, Yasuda T, Satoh R, Yoshida H, Kubo M, Kawamoto H, Koseki H, Taniguchi M PLoS Biol., 10(2), e1001255 (2012). 22346732 |
Health Report | |
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Examination Date / Room / Rack |
Gene | |||||||
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Gene Symbol | Gene Name | Chr. | Allele Symbol | Allele Name | Common Names | Promoter | Diseases Related to This Gene |
Il17rb MGI:1355292 | interleukin 17 receptor B | 14 | Il17rb<tm1Tgi> MGI:5426267 | targeted mutation 1, Masaru Taniguchi | |||
loxP | phage P1 loxP | 14 | loxP | ||||
loxP | phage P1 loxP | 14 | loxP | ||||
neo | neomycin resistance gene | 14 | mouse phosphoglycerate kinase promoter (PGK promoter) | ||||
SV40 polyA | 14 |
Phenotype | |
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Annotation by Mammalian phenotyhpe ontology | more 5 phenotypes |
Detailed phenotype data |
Ordering Information | |
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Donor DNA | Phage P1 loxP sites, mouse phosphoglycerate kinase promoter (PGK promoter), E. coli neomycin resistance gene, SV40 Poly A, mouse Il17rb genomic DNA |
Research application | Cre/loxP system |
Specific Term and Conditions | In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested. PLoS Biol. 10(2), e1001255, (2012). |
Depositor | Masaru Taniguchi (RIKEN) |
Strain Status | ![]() ![]() |
Strain Availability | Recovered litters from cryopreserved embryos (2 to 4 months) Cryopreserved sperm (within 1 month) Cryopreserved embryos (within 1 month) |
Additional Info. | Necessary documents for ordering:
Genotyping protocol -PCR- |
BRC mice in Publications |
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No Data |