RBRC10231

Information1

Image
BRC No.RBRC10231
TypeTargeted MutationCartagena
SpeciesMus musculus
Strain nameC.129S6-Bcl2l12/Irf3<tm1Ttg>
Former Common name
H-2 Haplotype
ES Cell lineCCE/EK.CCE [129S/SvEv-Gpi1<c>]
Background strain
Appearance
Strain developmentDeveloped and deposited by Dr. Steven N. Emancipator, Case Western Reserve University in 2018.
Strain descriptionIrf3 deficient mice. This is a BABL/c congenic strain by crossing RBRC00858 (B6;129S6-Bcl2l12/Irf3<tm1Ttg>/TtgRbrc) to BABL/cJ for 14 generations.
Colony maintenance
References

Health Report

Examination Date / Room / Rack2020/03/30Room:4-BRack:G
2020/01/27Room:4-BRack:G
2019/12/09Room:4-BRack:G
2019/11/25Room:4-BRack:G
2019/09/30Room:4-BRack:G
2019/07/29Room:4-BRack:G
2019/05/27Room:4-BRack:G
2019/03/25Room:4-BRack:G

Gene

Gene info
Gene symbolGene nameChr.Allele symbolAllele namePromoter
Irf3interferon regulatory factor 37Irf3<tm1Ttg>targeted mutation 1, Tadatsugu Taniguchi

Gene symbolGene nameChr.Allele symbolAllele namePromoter
Bcl2l12BCL2-like 12 (proline rich)7Bcl2l12<tm1Ttg>targeted mutation 1, Tadatsugu Taniguchi

Gene symbolGene nameChr.Allele symbolAllele namePromoter
neoneomycin resistance gene (E. coli)7mouse phosphoglycerate kinase promoter (PGK promoter)

Information2

Donor DNAmouse phosphoglycerate kinase promoter (PGK promoter), E. coli neo, mouse IRF-3 genomic DNA, mouse Bcl2l12 genomic DNA
Research applicationImmunology and Inflammation Research
Specific Term and ConditionsIn publishing the research results to be obtained by use of the BIOLOGICAL RESOURCE, an acknowledgment to the DEPOSITOR is requested. The RECIPIENT agrees to use the BIOLOGICAL RESOURSE only for publication of research papers. In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested. In publishing the research results to be obtained by use of the BIOLOGICAL RESOURCE, an acknowledgment to the DEPOSITOR is requested. The RECIPIENT of BIOLOGICAL RESOURCE must obtain a prior written consent on use of it from the DEPOSITOR/DEVELOPER.The RECIPIENT must contact the DEPOSITOR in the case of application for any patents or commercial use with the results from the use of the BIOLOGICAL RESOURSE.
DepositorSteven N. Emancipator (Case Western Reserve University)
Strain Statusan icon for Frozen embryosFrozen embryos
an icon for Frozen spermFrozen sperm
Strain AvailabilityCryopreserved embryos (within 1 month)
Live mouse (1 to 3 months)
Additional Info.Genotyping protocol -PCR-

BRC mice in Publications

No Data