Strain Data Sheet



BRC No.RBRC10072
SpeciesMus musculus
Strain nameC57BL/6-Tg(S100A8-FCGR2A<*>A225I)1Homy
Former Common nameMRP8/hFcgRIIa A225I Tg
H-2 Haplotype
ES Cell line
Background strain
Strain developmentDeveloped by Hiroaki Honda, Research Institute for Radiation Biology and Medicine, Hiroshima University in 2015. C57BL/6J genetic background.
Strain descriptionTransgenic mice expressing human FCGR2A with a point mutation (A225I) under the control of the human MRP8 (S100A8) promoter.
Colony maintenance

Health Report

Examination Date / Room / Rack


Gene info
Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter
FCGR2AFc receptor, IgG, low affinity II-aUNFCGR2Ahuman MRP8 promoter


Donor DNAhuman MRP8 promoter, human FcgRIIa A225I mutant cDNA [Update June, 10, 2020]
Research application
Specific Term and ConditionsPrior to requesting the BIOLOGICAL RESOURCE, the RECIPIENT must obtain approval from the DEPOSITOR using the Approval Form.
DepositorHiroaki Honda (Tokyo Women's Medical University)
Strain Statusan icon for Frozen spermFrozen sperm
Strain AvailabilityRecovered litters from cryopreserved sperm (2 to 4 months)
Cryopreserved sperm (within 1 month)
Additional Info.Genotyping protocol -PCR-
Necessary documents for ordering:
  1. Approval form (Japanese / English)
  2. Order form (Japanese / English)
  3. Category I MTA: MTA for distribution with RIKEN BRC (Japanese / English)
  4. Acceptance of responsibility for living modified organism (Japanese / English)
Lab HP (Japanese)

BRC mice in Publications

No Data