RBRC10063

Information1

Image
BRC No.RBRC10063
TypeTargeted MutationCartagena
SpeciesMus musculus
Strain nameC57BL/6J-Foxp3<tm1(CD2/CD52)Shori>
Former Common nameB6.Foxp3hCD2
H-2 Haplotype
ES Cell line
Background strainC57BL/6JJcl
Appearance
Strain development
Strain description
Colony maintenance
ReferencesImmunity. 2012 Feb 24;36(2):262-75. doi: 10.1016/j.immuni.2011.12.012. Epub 2012 Feb 9. 22326580

Health Report

Examination Date / Room / Rack2020/02/17Room:3-BRack:A
2019/12/16Room:3-BRack:A
2019/10/21Room:3-BRack:A
2019/08/26Room:3-BRack:A
2019/06/17Room:3-BRack:A
2019/04/15Room:3-BRack:A
2019/02/18Room:3-BRack:A
2018/12/17Room:3-BRack:A

Gene

Gene info
Gene symbolGene nameChr.Allele symbolAllele namePromoter
Foxp3forkhead box P3XFoxp3<tm1(CD2/CD52)Shori>targeted mutation 1, Shohei Hori

Gene symbolGene nameChr.Allele symbolAllele namePromoter
CD2XCD2

Gene symbolGene nameChr.Allele symbolAllele namePromoter
CD52CD52 antigenXCD52

Gene symbolGene nameChr.Allele symbolAllele namePromoter
Iresinternal ribosomal entry site (EMCV)X

Gene symbolGene nameChr.Allele symbolAllele namePromoter
loxPphage P1 loxPXloxP

Information2

Donor DNAEncephalomyocarditis virus (EMCV) internal ribosomal entry site (ires), human CD2 cDNA, human CD52 cDNA, Enterobacteria phage P1 loxP site, mouse Foxp3 genomic DNA
Research applicationCre/loxP system
Specific Term and ConditionsIn publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested. Immunity. 2012 Feb 24;36(2):262-75. doi: 10.1016/j.immuni.2011.12.012. Epub 2012 Feb 9.In publishing the research results to be obtained by use of the BIOLOGICAL RESOURCE, an acknowledgment to the DEPOSITOR is requested. The availability of the BIOLOGICAL RESOURCE is limited to a RECIPIENT of a not-for profit institution for a not-for-profit research.
DepositorShohei Hori (RIKEN)
Strain Statusan icon for Frozen embryosFrozen embryos
an icon for Frozen spermFrozen sperm
Strain AvailabilityRecovered litters from cryopreserved embryos (2 to 4 months)
Cryopreserved sperm (within 1 month)
Cryopreserved embryos (within 1 month)
Additional Info.Genotyping protocol -PCR-

BRC mice in Publications

No Data