Strain Data Sheet

RBRC10021

Information1

Image
BRC No.RBRC10021
TypeTransgeneCartagena
SpeciesMus musculus
Strain nameC57BL/6-Tg(Myh6-Kcnj8<*>S422L)111Hnky
Former Common nameKir6.1-TGmt#111
H-2 Haplotype
ES Cell line
Background strain
Appearance
Strain developmentDeveloped by Haruaki Nakaya, Chiba University. C57BL/6 genetic background. Next generation should be obtained by crossing TG males to wild-type females.
Strain descriptionTransgenic mice expressing rat mutated Kcnj8 (S422L) under the control of mouse Myh6 (myosin, heavy polypeptide 6, cardiac muscle, alpha) promoter.
Colony maintenance
ReferencesSci. Rep., 8(1):11723 (2018). 30082733

Health Report

Examination Date / Room / Rack

Gene

Gene info
Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter
GHGrowth hormone polyA (human)UNGH

Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter
Kcnj8potassium inwardly-rectifying channel, subfamily J, member 8 (rat)UNKcnj8mouse Myh6 promoter

Information2

Donor DNAmouse (APH)II MyHC promoter, Rat KCNJ8 cDNA(C420N, P421T, S422L), human GH polyA
Research applicationCardiovascular Research
Diabetes and Obesity Research
covid19_progression
Specific Term and ConditionsPrior to requesting the BIOLOGICAL RESOURCE, the RECIPIENT must obtain approval from the DEPOSITOR using the Approval Form. The RECIPIENT must contact the DEPOSITOR in the case of application for any patents or commercial use based on the results from the use of the BIOLOGICAL RESOURCE.
DepositorHaruki Nakaya (Chiba University)
Strain Statusan icon for Frozen spermFrozen sperm
Strain AvailabilityRecovered litters from cryopreserved sperm (2 to 4 months)
Cryopreserved sperm (within 1 month)
Additional Info.Necessary documents for ordering:
  1. Approval form (Japanese / English)
  2. Order form (Japanese / English)
  3. Category I MTA: MTA for distribution with RIKEN BRC (Japanese / English)
  4. Acceptance of responsibility for living modified organism (Japanese / English)

BRC mice in Publications

No Data