Strain Data Sheet


Strain Information

BRC No.RBRC09696
SpeciesMus musculus
Strain nameC57BL/6J-Tg(SFTPC-CD74/ROS1)125Tno
Former Common name#125
H-2 Haplotype
ES Cell line
Background strainC57BL/6JJcl
Strain developmentDeveloped by Tetsuo Noda, The Cancer Institute of JFCR. C57BL/6J background.
Strain descriptionMice model for the lung adenocarcinoma. Transgenice mice expressing CD74-ROS1 fusion protein under the control of the human SPC promoter.
Colony maintenance
ReferencesCarcinogenesis, 37, 452-460 (2016). 26964870

Health Report

Examination Date / Room / Rack


Gene info
Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter
CD74CD74 antigen (human)UNCD74human SFTPC promoter

Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter
FLAGFLAG tag (synthetic)UNFLAG

Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter
ROS1Ros1 proto-oncogene (human)UNROS1

Ordering Information

Donor DNAhuman SFTPC promoter, Flag tag (synthetic), human CD74 cDNA, human ROS1 cDNA, SV40 Splicing and Poly(A)
Research applicationCancer Research
Specific Term and ConditionsIn publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested. Carcinogenesis, 37, 452-460 (2016).For use of the BIOLOGICAL RESOURCE by a for-profit institution, the RECIPIENT must reach agreement on terms and conditions of use of it with DEPOSITOR and must obtain a prior written consent from the DEPOSITOR. The RECIPIENT must contact the DEPOSITOR in the case of application for any patents or commercial use based on the results from the use of the BIOLOGICAL RESOURCE.
DepositorTetsuo Noda (Japanese Foundation For Cancer Research)
Strain Statusan icon for Frozen spermFrozen sperm
Strain AvailabilityRecovered litters from cryopreserved sperm (2 to 4 months)
Cryopreserved sperm (within 1 month)
Additional Info.Necessary documents for ordering:
  1. Order form (Japanese / English)
  2. Category I MTA: MTA for distribution with RIKEN BRC (Japanese / English)
  3. Acceptance of responsibility for living modified organism (Japanese / English)

Genotyping protocol -PCR-

BRC mice in Publications

No Data