Strain Information | |
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Image | |
BRC No. | RBRC09599 |
Type | Targeted Mutation![]() |
Species | Mus musculus |
Strain name | FVB.129S6-Cd109<tm1Mat> |
Former Common name | CD109-KO |
H-2 Haplotype | |
ES Cell line | CSL3[129S6/SvEvTac] |
Background strain | FVB/NJcl |
Appearance | |
Strain development | |
Strain description | |
Colony maintenance | |
References | Epidermal hyperplasia and appendage abnormalities in mice lacking CD109. Mii S, Murakumo Y, Asai N, Jijiwa M, Hagiwara S, Kato T, Asai M, Enomoto A, Ushida K, Sobue S, Ichihara M, Takahashi M Am. J. Pathol, 181(4), 1180-1189 (2012). 22846721Suppression of skin tumorigenesis in CD109-deficient mice. Sunagawa M, Mii S, Enomoto A, Kato T, Murakumo Y, Shiraki Y, Asai N, Asai M, Nagino M, Takahashi M Oncotarget, 2016 Oct 14. doi: 10.18632/oncotarget.12653. 27756876 |
Health Report | |
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Examination Date / Room / Rack |
Gene | |||||||
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Gene Symbol | Gene Name | Chr. | Allele Symbol | Allele Name | Common Names | Promoter | Diseases Related to This Gene |
Cd109 MGI:2445221 | CD109 antigen | 9 | Cd109<tm1Mat> MGI:5443927 | targeted mutation 1, Masahide Takahashi | |||
HBB | human beta-globin polyA | 9 | HBB | ||||
lacZ | beta-galactosidase (E. coli) | 9 | |||||
neo | neomycin resistance gene (E. coli) | 9 | mouse phosphoglycerate kinase promoter (PGK promoter) | ||||
nls | SV40 large T antigen nuclear localization signal (NLS) | 9 | nls |
Phenotype | |
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Annotation by Mammalian phenotyhpe ontology | more 16 phenotypes |
Detailed phenotype data |
Ordering Information | |
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Donor DNA | nuclear localization signal, E. coli lacZ gene, Mouse phosphoglycerate kinase (PGK) promoter, E. coli neomycin resistance gene, Human beta-globin polyA, Mouse Cd109 genomic DNA |
Research application | Fluorescent Proteins/lacZ System |
Specific Term and Conditions | Prior to requesting the BIOLOGICAL RESOURCE, the RECIPIENT must obtain approval from the DEPOSITOR using the Approval Form. In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested. Oncotarget, 2016 Oct 14. doi: 10.18632/oncotarget.12653.The RECIPIENT must contact the DEPOSITOR in the case of application for any patents or commercial use based on the results from the use of the BIOLOGICAL RESOURCE. |
Depositor | Masahide Takahashi (Nagoya University) |
Strain Status | ![]() ![]() |
Strain Availability | Recovered litters from cryopreserved embryos (2 to 4 months) Cryopreserved embryos (within 1 month) |
Additional Info. | Necessary documents for ordering:
Genotyping protocol -PCR- |
BRC mice in Publications |
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No Data |