RBRC09517

Information1

Image
BRC No.RBRC09517
TypeCRISPR/Cas9 (Transgene)Cartagena
SpeciesMus musculus
Strain nameC57BL/6J-Inhbc<em61Ohm>
Former Common nameCas9-Inhbc
H-2 Haplotype
ES Cell line
Background strainC57BL/6JJcl
Appearance
Strain development2014年、北里大学 獣医学部 橋本 統 先生と産業技術総合研究所 栗崎 晃 博士との共同開発。C57BL/6J(日本クレア)とへテロの交配。
Strain descriptionInhibin/activin beta C subunit 遺伝子(Inhbc)のKOマウス。行動異常、代謝異常を示す。
Colony maintenance
References

Health Report

Examination Date / Room / RackNo Data

Gene

Gene info
Gene symbolGene nameChr.Allele symbolAllele namePromoter
Inhbcinhibin beta-C10Inhbc<em61Ohm>endonuclease-mediated mutation 61, Osamu Hashimoto

Information2

Donor DNAマウス Inhibin/activin beta C subunit (Inhbc), ヒト hU6 promoter, ウシ bGH poly A, cytomegalovirus CMV promoter, Simian virus 40 Nuclear localization signal, Streptococcus pyogenes Cas9, CRISPER, trans-activating CRISPER, E. coli pBR322 ori
Research application
Specific Term and ConditionsPrior to requesting the BIOLOGICAL RESOURCE, the RECIPIENT must obtain approval from the DEPOSITOR using the Approval Form.
DepositorOsamu Hashimoto (The Kitasato Institute)
Strain Statusan icon for Frozen spermFrozen sperm
Strain AvailabilityRecovered litters from cryopreserved sperm (2 to 4 months)
Cryopreserved sperm (within 1 month)
Additional Info.Genotyping protocol -PCR-

BRC mice in Publications

No Data