Strain Data Sheet

RBRC09487

Strain Information

Image
BRC No.RBRC09487
TypeTransgeneCartagena
SpeciesMus musculus
Strain nameC57BL/6N-Tyr<c-Brd>-Tg(IL6-Luc)
Former Common namehIL6-BAC-Luc
H-2 Haplotype
ES Cell line
Background strain
Appearance
Strain development
Strain description
Colony maintenance
References
Whole-Body In Vivo Monitoring of Inflammatory Diseases Exploiting Human Interleukin 6-Luciferase Transgenic Mice.
Hayashi M, Takai J, Yu L, Motohashi H, Moriguchi T, Yamamoto M
Mol. Cell Biol., 35(20):3590-601 (2015). 26283726

Health Report

Examination Date / Room / Rack

Gene

Gene SymbolGene NameChr.Allele SymbolAllele NameCommon NamesPromoterDiseases Related to This Gene
Frt yeast FRT (flippase recombination target) site7Frt
Tyr
MGI:98880		tyrosinase7Tyr<c-Brd>
MGI:3640303		albino, Allan Bradley
  • oculocutaneous albinism type 1A(DisGeNET, MedGEN)

  • oculocutaneous albinism type 1B(MedGEN)

  • oculocutaneous albinism(DisGeNET)
    • loxP phage P1 loxPUNloxP
    luc luciferaseUNluc human IL6 promoter
    SV40 polyAUN

    Phenotype

    Phenotype annotation from literatures by Mammalian phenotype ontology
  • normal phenotype (MP:0002873)
    • Detailed phenotype data

    Ordering Information

    Donor DNAhuman IL6 locus genomic DNA (BAC clone RP11-469J8), firefly luciferase cDNA, SV40 late polyA signal, yeast FRT (flipase recombination target) site, Phage P1 loxP site
    Research applicationCre/loxP system
    FLP/frt system
    Immunology and Inflammation Research
    covid19_onset
    Specific Term and ConditionsPrior to requesting the BIOLOGICAL RESOURCE, the RECIPIENT must obtain approval from the DEPOSITOR using the Approval Form. In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested. Mol. Cell Biol., 35(20):3590-601 (2015).In publishing the research results to be obtained by use of the BIOLOGICAL RESOURCE, involving the DEPOSITOR in author byline is requested (by Aug 2017).
    DepositorMasayuki Yamamoto (Tohoku University)
    Strain Statusan icon for Frozen embryosFrozen embryos
    an icon for Frozen spermFrozen sperm
    Strain AvailabilityRecovered litters from cryopreserved embryos (2 to 4 months)
    Cryopreserved sperm (within 1 month)
    Cryopreserved embryos (within 1 month)
    Additional Info.Necessary documents for ordering:
    1. Approval form (Japanese / English)
    2. Order form (Japanese / English)
    3. Category I MTA: MTA for distribution with RIKEN BRC (Japanese / English)
    4. Acceptance of responsibility for living modified organism (Japanese / English)

    Genotyping protocol -PCR-
    Mouse of the Month May 2016

    BRC mice in Publications

    No Data