RBRC09446

Information1

Image
BRC No.RBRC09446
TypeTargeted MutationCartagena
SpeciesMus musculus
Strain nameC57BL/6-Islr<tm1a(EUCOMM)Wtsi>/Ea
Former Common nameIslr KO
H-2 Haplotype
ES Cell lineJM8A3.N1 [C57BL/6N-A<tm1Brd>]
Background strain
Appearance
Strain development
Strain description
Colony maintenance
ReferencesCancer Res., 79(20):5367-5381 (2019). 31439548
Sci. Rep., 6:22288 (2016). 26924503
Genomics., 44, 273-279 (1997). 9325048
Circ. Res.,125(4):414-430 (2019). 31221024

Health Report

Examination Date / Room / RackNo Data

Gene

Gene info
Gene symbolGene nameChr.Allele symbolAllele namePromoter
Islrimmunoglobulin superfamily containing leucine-rich repeat9Islr<tm1a(EUCOMM)Wtsi>targeted mutation 1a, Wellcome Trust Sanger Institute

Gene symbolGene nameChr.Allele symbolAllele namePromoter
En2En2 SA (mouse En2 intron 2/exon 3 splice acceptor sequence)9En2

Gene symbolGene nameChr.Allele symbolAllele namePromoter
Frtyeast FRT (flippase recombination target) site9Frt

Gene symbolGene nameChr.Allele symbolAllele namePromoter
Frtyeast FRT (flippase recombination target) site9Frt

Gene symbolGene nameChr.Allele symbolAllele namePromoter
Iresinternal ribosomal entry site (EMCV)9

Gene symbolGene nameChr.Allele symbolAllele namePromoter
SASplice acceptor9SA

Gene symbolGene nameChr.Allele symbolAllele namePromoter
lacZbeta-galactosidase (E. coli)9

Gene symbolGene nameChr.Allele symbolAllele namePromoter
loxPphage P1 loxP9loxP

Gene symbolGene nameChr.Allele symbolAllele namePromoter
loxPphage P1 loxP9loxP

Gene symbolGene nameChr.Allele symbolAllele namePromoter
loxPphage P1 loxP9loxP

Gene symbolGene nameChr.Allele symbolAllele namePromoter
neoneomycin resistance gene (E. coli)9human beta-actin promoter

Gene symbolGene nameChr.Allele symbolAllele namePromoter
SV40 PolyA signal9

Information2

Donor DNAyeast FRT (flipase recombination target) sites, En2 SA (mouse En2 intron 2/exon 3 splice acceptor sequence), Encephalomyocarditis virus (EMCV) internal ribosomal entry site (ires), E. coli lacZ, SV40 polyadenylation site, phage P1 loxP sites, hBactP (human beta actin promoter), E. coli neo, mouse Islr genomic DNA
Research applicationCre/loxP system
FLP/frt system
Fluorescent Proteins/lacZ System
Specific Term and ConditionsIn publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested. Sci. Rep., 6:22288 (2016). Circ. Res.,125(4):414-430 (2019). Cancer Res., in press (2019).This strain was established by the DEPOSITOR by using knockout ES cells of EUCOMM Consortium. The RECIPIENT shall acknowledge the EUCOMM Consortium as the source of the ES cells and the DEPOSITOR for providing the strain. The strain shall only be used for non-commercial purposes.
DepositorAtsushi Enomoto (Nagoya University)
Strain Statusan icon for Frozen spermFrozen sperm
Strain AvailabilityRecovered litters from cryopreserved sperm (2 to 4 months)
Cryopreserved sperm (within 1 month)
Additional Info.

BRC mice in Publications

No Data