BRC No.RBRC09443
TypeChemically-induced Mutation
SpeciesMus musculus
Strain nameC3.B6-Tuba1a<Rgsc1736>
Former Common nameM1001736
H-2 Haplotype
ES Cell line
Background strain
Strain development
Strain descriptionThe founder mouse of M1-1736 exhibited an increased spontaneous-locomotor activity in open field and home cage. The mutant carries missense mutation in the Tuba1a. The heterozygote exhibited inattention to novel object and, disorganized structure of cerebral neocortex. The attention deficit and hyperactivity were improved by methylphenidate injection.
Colony maintenance
ReferencesBehav. Brain Res., 227, 167-174 (2012). 22101068

Health Report

Examination Date / Room / RackNo Data


Gene info
Gene symbolGene nameChr.Allele symbolAllele namePromoter
Tuba1atubulin, alpha 1A15Tuba1a<Rgsc1736>RIKEN Genomic Sciences Center (GSC), 1736


Donor DNA
Research applicationDevelopmental Biology Research
Specific Term and ConditionsIn publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested. Behav. Brain Res., 227, 167-174 (2012).The RECIPIENT of for-profit institution must contact the DEPOSITOR separately.
The RECIPIENT of not for-profit institution must contact and discuss in good faith with the DEPOSITOR regarding inventorship, ownership, patent filing and licese fees and others, prior to filing a patent or make a contract with license fees with a third party for invention or products obtained from research results by using the BIOLOGICAL RESOURCES.
Strain Statusan icon for Frozen spermFrozen sperm
Strain AvailabilityRecovery and QC required prior to distribution
Additional Info.

BRC mice in Publications

No Data