Strain Data Sheet

RBRC09401

Strain Information

Image
BRC No.RBRC09401
TypeTargeted MutationCartagena
SpeciesMus musculus
Strain nameB6.CBA-Psme4<tm1Tchi>
Former Common namePA200 KO
H-2 Haplotype
ES Cell lineTT2 [(C57BL/6NCrlj x CBA/JNCrlj)F1]
Background strainC57BL/6JJcl
Appearance
Strain development
Strain description
Colony maintenance
References
Acetylation-mediated proteasomal degradation of core histones during DNA repair and spermatogenesis.
Qian M X, Pang Y, Liu C H, Haratake K, Du B Y, Ji D Y, Wang G F, Zhu Q Q, Song W, Yu Y, Zhang X X, Huang H T, Miao S, Chen L B, Zhang Z H, Liang Y N, Liu S, Cha H, Yang D, Zhai Y, Komatsu T, Tsuruta F, Li H, Cao C, Li W, Li G H, Cheng Y, Chiba T, Wang L, Goldberg A L, Shen Y, Qiu X B
Cell., 153(5), 1012-1024 (2013). 23706739

Health Report

Examination Date / Room / Rack

Gene

Gene SymbolGene NameChr.Allele SymbolAllele NameCommon NamesPromoterDiseases Related to This Gene
Psme4proteasome (prosome, macropain) activator subunit 411Psme4targeted mutation 1, Tomoki Chiba
neoneomycin resistance gene (E. coli)11mouse phosphoglycerate kinase promoter (PGK promoter)

Phenotype

Annotation by Mammalian phenotyhpe ontology
  • abnormal male germ cell apoptosis(MP:0008280)

  • abnormal spermatid morphology(MP:0006380)

  • reduced male fertility(MP:0001922)
    • Detailed phenotype data

    Ordering Information

    Donor DNAmouse phosphoglycerate kinase promoter (PGK promoter), E. coli Neomycin resistance gene, mouse Psme4 genomic DNA
    Research applicationCell Biology Research
    Developmental Biology Research
    Specific Term and ConditionsIn publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested. Cell., 153(5), 1012-1024 (2013). In publishing the research results to be obtained by use of the BIOLOGICAL RESOURCE, an acknowledgment to the DEPOSITOR is requested. The RECIPIENT must contact with the DEPOSITOR and discuss about collaboration prior to use the BIOLOGICAL RESOURCE.
    DepositorTomoki Chiba (University of Tsukuba)
    Strain Statusan icon for Frozen embryosFrozen embryos
    an icon for Frozen spermFrozen sperm
    Strain AvailabilityRecovered litters from cryopreserved embryos (2 to 4 months)
    Cryopreserved embryos (within 1 month)
    Additional Info.Necessary documents for ordering:
    1. Order form (Japanese / English)
    2. Category I MTA: MTA for distribution with RIKEN BRC (Japanese / English)
    3. Acceptance of responsibility for living modified organism (Japanese / English)

    Genotyping protocol -PCR-

    BRC mice in Publications

    No Data