Strain Data Sheet

RBRC09236

Strain Information

Image
BRC No.RBRC09236
TypeTransgeneCartagena
SpeciesMus musculus
Strain nameB6.ICR-Tg(CDKN2A-luc)53Eiha/EihaRbrc
Former Common namep16-luc(B6), B6-p16-luc Tg, Human p16-luc mouse, p16-luc(Acc. No. CDB0416T-53)(B6)
H-2 Haplotype
ES Cell line
Background strainC57BL/6JJcl
Appearance
Strain developmentDeveloped by Eiji Hara, The Cancer Institute, Japanese Foundation for Cancer Research. The transgene was injected into the pronuclei of ICR fertilized eggs. The mutant mice were backcrossed to C57BL/6.
Strain descriptionhuman p16-luciferase transgenic mice.
Colony maintenanceCarrier x Noncarrier [C57BL/6JJcl]
References
Real-time in vivo imaging of p16Ink4a reveals cross talk with p53.
Yamakoshi K, Takahashi A, Hirota F, Nakayama R, Ishimaru N, Kubo Y, Mann D J, Ohmura M, Hirao A, Saya H, Arase S, Hayashi Y, Nakao K, Matsumoto M, Ohtani N, Hara E
J. Cell Biol., 186, 393-407 (2009). 19667129

Health Report

Examination Date / Room / Rack2024/08/19Room:4-ARack:G
2024/05/20Room:4-ARack:G
2024/02/19Room:4-ARack:G
2023/11/20Room:4-ARack:G
2023/08/21Room:4-ARack:G
2023/05/22Room:4-ARack:G
2023/03/22Room:4-ARack:G
2023/02/20Room:4-ARack:G

Gene

Gene SymbolGene NameChr.Allele SymbolAllele NameCommon NamesPromoterDiseases Related to This Gene
lucluciferaseUNluchuman CDKN2A promoter
neoneomycin resistance gene (E. coli)UN

Phenotype

Annotation by Mammalian phenotyhpe ontology
  • normal phenotype(MP:0002873)
    • Detailed phenotype data

    Ordering Information

    Donor DNAHuman CDKN2A (p16ink4) genomic DNA, Firefly luciferase cDNA, E. coli neo
    Research applicationCell Biology Research
    Specific Term and Conditions(1) The RECIPIENT shall obtain a prior agreement from the DEVELOPER (Dr. Eiji Hara, The Cancer Institute of Japanese Foundation for Cancer Research, E-mail:eiji.hara@jfcr.or.jp) to transfer the BIOLOGICAL RESOURCE. (2) In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the Acc.No. CDB0416T-53 and Web. Site (https://large.riken.jp/distribution/mutant-list.html) is requested. (3) In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the literature designed by the DEPOSITOR is requested. (J Cell Biol. 2009 186(3):393-407.) (4) Please inform the DEPOSITOR (mutant.bdr@riken.jp) about the paper when published.
    DepositorRIKEN CDB (RIKEN CDB)
    Strain Statusan icon for Live miceLive mice
    an icon for Frozen embryosFrozen embryos
    an icon for Frozen spermFrozen sperm
    Strain AvailabilityCryopreserved sperm (within 1 month)
    Cryopreserved embryos (within 1 month)
    Live mouse (1 to 3 months)
    Additional Info.Necessary documents for ordering:
    1. Order form (Japanese / English)
    2. Category I MTA: MTA for distribution with RIKEN BRC (Japanese / English)
    3. Acceptance of responsibility for living modified organism (Japanese / English)

    Genotyping protocol -PCR-

    BRC mice in Publications

    No Data