RBRC09236

Information1

Image
BRC No.RBRC09236
TypeTransgeneCartagena
SpeciesMus musculus
Strain nameB6.ICR-Tg(CDKN2A-luc)53Eiha/EihaRbrc
Former Common namep16-luc(B6), B6-p16-luc Tg, Human p16-luc mouse, p16-luc(Acc. No. CDB0416T-53)(B6)
H-2 Haplotype
ES Cell line
Background strainC57BL/6JJcl
Appearance
Strain developmentDeveloped by Eiji Hara, The Cancer Institute, Japanese Foundation for Cancer Research. The transgene was injected into the pronuclei of ICR fertilized eggs. The mutant mice were backcrossed to C57BL/6.
Strain descriptionhuman p16-luciferase transgenic mice.
Colony maintenanceCarrier x Noncarrier [C57BL/6JJcl]
ReferencesJ. Cell Biol., 186, 393-407 (2009). 19667129

Health Report

Examination Date / Room / Rack2020/03/30Room:4-ARack:G
2020/01/27Room:4-ARack:G
2019/11/25Room:4-ARack:G
2019/09/30Room:4-ARack:G
2019/07/29Room:4-ARack:G
2019/05/27Room:4-ARack:G
2019/03/25Room:4-ARack:G
2019/01/28Room:4-ARack:G

Gene

Gene info
Gene symbolGene nameChr.Allele symbolAllele namePromoter
lucluciferaseUNluchuman CDKN2A promoter

Gene symbolGene nameChr.Allele symbolAllele namePromoter
neoneomycin resistance gene (E. coli)UN

Information2

Donor DNAHuman CDKN2A (p16ink4) genomic DNA, Firefly luciferase cDNA, E. coli neo
Research applicationCell Biology Research
Specific Term and Conditions(1) The RECIPIENT shall obtain a prior agreement from the DEVELOPER (Dr. Eiji Hara, The Cancer Institute of Japanese Foundation for Cancer Research, E-mail:eiji.hara@jfcr.or.jp) to transfer the BIOLOGICAL RESOURCE. (2) In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the Acc.No. CDB0416T-53 and Web. Site (http://www2.clst.riken.jp/arg/mutant%20mice%20list.html) is requested. (3) In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the literature designed by the DEPOSITOR is requested. (J Cell Biol. 2009 186(3):393-407.) (4) Please inform the DEPOSITOR (mutant.bdr@riken.jp) about the paper when published.
DepositorRIKEN CDB (RIKEN CDB)
Strain Statusan icon for Live miceLive mice
an icon for Frozen spermFrozen sperm
Strain AvailabilityCryopreserved sperm (within 1 month)
Live mouse (1 to 3 months)
Additional Info.Genotyping protocol -PCR-

BRC mice in Publications

No Data