BRC No.RBRC06558
TypeChemically-induced Mutation
SpeciesMus musculus
Strain nameB6(D2)-Smo<Rgsc2073>
Former Common nameSmoG457X, B6-Smo/G457X
H-2 Haplotype
ES Cell line
Background strainC57BL/6JJcl
Strain developmentDeveloped by Shigeru Makino and Yoichi Gondo, RIKEN BioResource center. Generated by RIKEN ENU-based gene driven mutagenesis. The mutant mice were backcrossed to C57BL/6J.
Strain descriptionSmo gene G457X variant mice. Homozygous mutant mice die around E10.
Colony maintenanceHeterozygote x Wild-type [C57BL/6JJcl]
ReferencesNat Rev Genet., 9, 803-810 (2008). 18781157

Health Report

Examination Date / Room / RackNo Data


Gene info
Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter
Smosmoothened homolog (Drosophila)6Smo<Rgsc2073>RIKEN Genomic Sciences Center (GSC), 2073


Donor DNA
Research applicationCancer Research
Developmental Biology Research
Neurobiology Research
Specific Term and ConditionsIn publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested. 後日指定。(will be announced).
DepositorYoichi Gondo (RIKEN GSC)
Strain Statusan icon for Frozen spermFrozen sperm
Strain AvailabilityRecovered litters from cryopreserved sperm (2 to 4 months)
Additional Info.

BRC mice in Publications

No Data