BRC No.RBRC06542
TypeTargeted MutationCartagena
SpeciesMus musculus
Strain nameB6.Cg-Lrrc6<tm1.2Hmd>
Former Common nameLrrc6 null, B6-Lrrc6 KO
H-2 Haplotype
ES Cell lineG4 [(129S6/SvEvTac x C57BL/6NCr)F1]
Background strain
Strain developmentDeveloped by Katsura Minegishi and Hiroshi Hamada, Graduate School of Frontier Biosciences, Osaka University in 2010. G4 ES cells derived from (129 x C57BL/6)F1 were used to generate the mutant mice. Flanked Exon 1 was removed by crossing with CAG-Cre mice (B6/129 background). C57BL/6 and 129 mixed background.
Strain descriptionExon 1 of Lrrc6 gene was removed.
Colony maintenanceHeterozygote x Wild-type [C57BL/6JJcl]
ReferencesGenes to Cells, 21, 728-739 (2017). 27353389

Health Report

Examination Date / Room / Rack2019/09/30Room:4-ARack:K


Gene info
Gene symbolGene nameChr.Allele symbolAllele namePromoter
Lrrc6leucine rich repeat containing 6 (testis)15Lrrc6<tm1.2Hmd>targeted mutation 1.2, Hiroshi Hamada

Gene symbolGene nameChr.Allele symbolAllele namePromoter
loxPphage P1 loxP15loxP


Donor DNAphage P1 loxP site, mouse Lrrc6 genomic DNA
Research applicationCre/loxP system
Specific Term and ConditionsThe RECIPIENT of BIOLOGICAL RESOURCE shall obtain a prior written consent on use of it from the DEPOSITOR/DEVELOPER. RECIPIENT which wants to use the BIOLOGICAL RESOURCE for the purpose other than education or not-for-profit research is requested to enter into a Material Transfer Agreement with Osaka University.
DepositorHiroshi Hamada (RIKEN)
Strain Statusan icon for Frozen embryosFrozen embryos
an icon for Frozen spermFrozen sperm
Strain AvailabilityRecovered litters from cryopreserved sperm (2 to 4 months)
Cryopreserved sperm (within 1 month)
Additional Info.Genotyping protocol -PCR-

BRC mice in Publications

No Data