RBRC06534

Information1

Image
BRC No.RBRC06534
TypeTargeted MutationCartagena
SpeciesMus musculus
Strain nameB6;129S6-Fcrl6<tm1Csk>
Former Common nameNKIR KO, B6-Fcrl6 KO
H-2 Haplotype
ES Cell lineNot specified (ES cell)
Background strain
Appearance
Strain developmentDeveloped by Kouji Matsushima, Graduate School of Medicine, University of Tokyo and Chugai Pharmaceutical Co, Ltd. 129S6 derived ES cells were used to generate the mutant mice. C57BL/6 and 129 mixed background.
Strain descriptionNKIR (Fcrl6) gene knockout mice. From exon 3 to a part of exon 6 was replaced with a loxP-flanked neo cassette. Homozygous mutant mice show no obvious abnormality.
Colony maintenanceHomozygote x Homozygote [or Crossing to C57BL/6JJcl]
References

Health Report

Examination Date / Room / RackNo Data

Gene

Gene info
Gene symbolGene nameChr.Allele symbolAllele namePromoter
Fcrl6Fc receptor-like 61Fcrl6<tm1Csk>targeted mutation 1, Chugai Pharmaceutical Co, Ltd

Gene symbolGene nameChr.Allele symbolAllele namePromoter
loxPphage P1 loxP1loxP

Gene symbolGene nameChr.Allele symbolAllele namePromoter
loxPphage P1 loxP1loxP

Gene symbolGene nameChr.Allele symbolAllele namePromoter
neoneomycin resistance gene (E. coli)1mouse phosphoglycerate kinase promoter (PGK promoter)

Information2

Donor DNAmouse phosphoglycerate kinase promoter (PGK promoter), E. coli neo, Phage P1 loxP, mouse Fcrl6 genomic DNA
Research applicationCre/loxP system
Immunology and Inflammation Research
Specific Term and ConditionsPrior to requesting the BIOLOGICAL RESOUCE, the RECIPIENT shall obtain a written consent from the DEPOSITTOR and its co-developer (Dr. Kou-ichi Jishage: jishagekui@chugai-pharm.co.jp, Chugai Pharmaceutical Co., Ltd. and Professor Kouji Matsushima: koujim@rs.tus.ac.jp) and, if necessary, shall enter into a material transfer agreement with their institutes.
DepositorDrs. Kouji Matsushima and Kou-ichi Jishage (The University of Tokyo/ Chugai Pharmaceutical Co., Ltd.)
Strain Statusan icon for Frozen spermFrozen sperm
Strain AvailabilityRecovery and QC required prior to distribution
Additional Info.

BRC mice in Publications

No Data