RBRC06532

Information1

Image
BRC No.RBRC06532
TypeTargeted MutationCartagena
SpeciesMus musculus
Strain nameB6.Cg-Jmjd1c<tm1Mtac>
Former Common nameJmjd1c KO, B6-Jmjd1c KO
H-2 Haplotype
ES Cell lineTT2 [(C57BL/6NCrlj x CBA/JNCrlj)F1]
Background strain
Appearance
Strain developmentDeveloped by Matoko Tachibana, Institute for Virus Research, Kyoto Uiniversity in 2008. TT2 ES cells were used to generate the mutant mice. C57BL/6 semicongenic.
Strain descriptionJmjd1c gene knockout mice. Exons 24 to 57 was replaced with an IRES-neo cassette.
Colony maintenanceHeterozygote x Wild-type [C57BL/6JJmsSlc]
ReferencesBiology of reproduction 89(4):93,1-9 (2013). 24006281

Health Report

Examination Date / Room / Rack2015/11/30Room:4-ARack:J
2015/09/28Room:4-ARack:J
2015/07/27Room:4-ARack:J
2015/05/25Room:4-ARack:J
2015/04/08Room:4-ARack:J
2015/04/06Room:4-ARack:J
2015/03/23Room:4-ARack:J

Gene

Gene info
Gene symbolGene nameChr.Allele symbolAllele namePromoter
Jmjd1cjumonji domain containing 1C10Jmjd1c<tm1Mtac>targeted mutation 1, Makoto Tachibana

Gene symbolGene nameChr.Allele symbolAllele namePromoter
IRESinternal ribosomal entry site (EMCV)10

Gene symbolGene nameChr.Allele symbolAllele namePromoter
neoneomycin resistance gene (Streptomyces fradiase)10

Gene symbolGene nameChr.Allele symbolAllele namePromoter
SV40 polyA signal10

Information2

Donor DNAStreptomyces fradiase neo, Encephalomyocarditis virus (EMCV) internal ribosomal entry site (ires), Simian virus 40 polyA additional signal, mouse jumonji domain containing 1C genomic DNA
Research application
Specific Term and ConditionsIn publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested. Biology of reproduction, 89(4):93,1-9 (2013).
DepositorMakoto Tachibana (Tokushima University)
Strain Statusan icon for Frozen spermFrozen sperm
Strain AvailabilityRecovered litters from cryopreserved sperm (2 to 4 months)
Cryopreserved sperm (within 1 month)
Additional Info.Genotyping protocol -PCR-

BRC mice in Publications

No Data