RBRC06516

Information1

Image
BRC No.RBRC06516
TypeTargeted MutationCartagena
SpeciesMus musculus
Strain nameB6.Cg-Tdrd7<tm1.1Chum>
Former Common nameT7 KO, B6-Tdrd7 KO
H-2 Haplotype
ES Cell lineKY1.1[(C57BL/6J x 129S6/SvEvTac)F1]
Background strain
Appearance
Strain developmentDeveloped by Shinichiro Chuma, Institute for Frontier Medical Sciences, Kyoto University in 2011. (C57BL/6J x 129S6/SvEvTac)F1 derived ES cells were used to generate the mutant mice. The mice were crossed to C57BL/6.
Strain descriptionTrd7 gene knockout mice. Male homozygous mice are sterile, displaying small testis with abnormal spermatid morphology. Exons 8-12 were removed by cre excision.
Colony maintenanceHeterozygote x Wild-type [C57BL/6JJcl]
ReferencesProc. Natl. Acad. Sci. USA, 28. 10579-10584 (2011). 21670278

Health Report

Examination Date / Room / RackNo Data

Gene

Gene info
Gene symbolGene nameChr.Allele symbolAllele namePromoter
Tdrd7tudor domain containing 74Tdrd7<tm1.1Chum>targeted mutation 1.1, Shinichiro Chuma

Gene symbolGene nameChr.Allele symbolAllele namePromoter
loxPphage P1 loxP4loxP

Information2

Donor DNAphage loxP site, mouse Tdrd7 genomic DNA
Research applicationCre/loxP system
Specific Term and ConditionsPrior to requesting the BIOLOGICAL RESOURCE, the RECIPIENT must obtain approval from the DEPOSITOR using the Approval Form.
DepositorShinichiro Chuma (Kyoto University)
Strain Statusan icon for Frozen embryosFrozen embryos
an icon for Frozen spermFrozen sperm
Strain AvailabilityRecovered litters from cryopreserved sperm (2 to 4 months)
Cryopreserved sperm (within 1 month)
Additional Info.Genotyping protocol -PCR-

BRC mice in Publications

No Data