RBRC06422

Information1

Image
BRC No.RBRC06422
TypeSpontaneous Mutation
SpeciesMus musculus
Strain nameBALB/c-Scn1a<+/->
Former Common nameC.Dravet, BALB-Scn1a
H-2 Haplotype
ES Cell line
Background strainBALB/cCrSlc
Appearance
Strain developmentDeveloped by Yoshibumi Matsushima, Saitama Cancer Center, Research Institute for Clinical Oncology.
Strain descriptionScn1a spontaneous mutant (Dravet syndrome) mice arose in BALB/c. Heterozygous mice show heat-induced epileptic seizure. Homozygous mutant mice show severe myoclonic epilepsy in infancy, and die at around 3 weeks old. Under investigation. BALB/cCrSlc background (semicongenic) (RBRC06422).
Colony maintenanceHeterozygote x Heterozygote [or Crossing to BALB/cCrSlc]
References

Health Report

Examination Date / Room / Rack2018/05/21Room:4-BRack:E
2018/03/26Room:4-BRack:E
2018/01/22Room:4-BRack:E
2017/11/27Room:4-BRack:E
2017/09/25Room:4-BRack:E
2017/07/24Room:4-BRack:E
2017/05/29Room:4-BRack:E
2017/03/27Room:4-BRack:E

Gene

Gene info
Gene symbolGene nameChr.Allele symbolAllele namePromoter
Scn1asodium channel, voltage-gated, type I, alpha2Scn1a

Information2

Donor DNA
Research applicationMouse Models for Human Disease
Neurobiology Research
Specific Term and ConditionsIn publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested. 後日指定。(will be announced.)For use of the BIOLOGICAL RESOURCE by a for-profit institution, the RECIPIENT must reach agreement on terms and conditions of use of it with DEPOSITOR and must obtain a prior written consent from the DEPOSITOR.
DepositorYoshibumi Matsushima (Saitama Cancer Center)
Strain Statusan icon for Frozen spermFrozen sperm
Strain AvailabilityRecovered litters from cryopreserved sperm (2 to 4 months)
Cryopreserved sperm (within 1 month)
Additional Info.

BRC mice in Publications

No Data