Strain Data Sheet


Strain Information

BRC No.RBRC06422
TypeSpontaneous Mutation
SpeciesMus musculus
Strain nameBALB/c-Scn1a<+/->
Former Common nameC.Dravet, BALB-Scn1a
H-2 Haplotype
ES Cell line
Background strainBALB/cCrSlc
Strain developmentDeveloped by Yoshibumi Matsushima, Saitama Cancer Center, Research Institute for Clinical Oncology.
Strain descriptionScn1a spontaneous mutant (Dravet syndrome) mice arose in BALB/c. Heterozygous mice show heat-induced epileptic seizure. Homozygous mutant mice show severe myoclonic epilepsy in infancy, and die at around 3 weeks old. Under investigation. BALB/cCrSlc background (semicongenic) (RBRC06422).
Colony maintenanceHeterozygote x Heterozygote [or Crossing to BALB/cCrSlc]

Health Report

Examination Date / Room / Rack


Gene info
Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter
Scn1asodium channel, voltage-gated, type I, alpha2Scn1a

Ordering Information

Donor DNA
Research applicationMouse Models for Human Disease
Neurobiology Research
Specific Term and ConditionsIn publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested. (will be announced.) For use of the BIOLOGICAL RESOURCE by a for-profit institution, the RECIPIENT must reach agreement on terms and conditions of use of it with DEPOSITOR and must obtain a prior written consent from the DEPOSITOR.
DepositorYoshibumi Matsushima (Saitama Cancer Center)
Strain Statusan icon for Frozen embryosFrozen embryos
an icon for Frozen spermFrozen sperm
Strain AvailabilityRecovered litters from cryopreserved sperm (2 to 4 months)
Cryopreserved sperm (within 1 month)
Additional Info.Necessary documents for ordering:
  1. Order form (Japanese / English)
  2. Category I MTA: MTA for distribution with RIKEN BRC (Japanese / English)

Genotyping protocol -PCR-

BRC mice in Publications

No Data