RBRC06410

Information1

Image
BRC No.RBRC06410
TypeTargeted MutationCartagena
SpeciesMus musculus
Strain nameB6.Cg-Nfkbiz<tm1.1Muta>
Former Common nameIκB-ζ flox/flox, B6-Nfkbiz floxed
H-2 Haplotype
ES Cell lineBruce 4 [B6.Cg-Thy1<a>]
Background strain
Appearance
Strain developmentDeveloped by Tatsushi Muta, Graduate School of Life Sciences, Tohoku University. Bruce 4 ES cells were used to generate the mutant mice. A frt-neo cassette was removed by crossing with CAG-FLPe (B6) mice.
Strain descriptionNfkbiz gene floxed mice. Exons 5 to 7 were flanked by loxP sites.
Colony maintenanceHomozygote x Homozygote [or Crossing to C57BL/6JJmsSlc]
ReferencesImmunity, 38, 450-460 (2013). 23453632

Health Report

Examination Date / Room / Rack2020/06/01Room:3-BRack:L
2020/02/17Room:3-BRack:L
2019/12/16Room:3-BRack:L
2019/10/21Room:3-BRack:L
2019/08/26Room:3-BRack:L
2019/06/17Room:3-BRack:L
2019/04/15Room:3-BRack:L
2019/04/08Room:3-BRack:L

Gene

Gene info
Gene symbolGene nameChr.Allele symbolAllele namePromoter
Nfkbiznuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, zeta16Nfkbiz<tm1.1Muta>targeted mutation 1.1, Tatsushi Muta

Gene symbolGene nameChr.Allele symbolAllele namePromoter
Frtyeast FRT (flippase recombination target) site16Frt

Gene symbolGene nameChr.Allele symbolAllele namePromoter
loxPphage P1 loxP16loxP

Gene symbolGene nameChr.Allele symbolAllele namePromoter
loxPphage P1 loxP16loxP

Information2

Donor DNAP1 phage loxP sites, yeast FRT (flippase recombination target) site, mouse Nfkbiz genomic DNA
Research applicationCre/loxP system
FLP/frt system
Specific Term and ConditionsPrior to requesting the BIOLOGICAL RESOURCE, the RECIPIENT must obtain approval from the DEPOSITOR using the Approval Form.
DepositorTakashi Maruyama (Gifu University)
Strain Statusan icon for Live miceLive mice
an icon for Frozen embryosFrozen embryos
an icon for Frozen spermFrozen sperm
Strain AvailabilityCryopreserved sperm (within 1 month)
Live mouse (1 to 3 months)
Additional Info.Genotyping protocol -PCR-
Mouse of the Month Apr 2017

BRC mice in Publications

No Data