BRC No.RBRC06395
TypeTargeted MutationCartagena
SpeciesMus musculus
Strain nameB6;129P2-Fbxw7<tm2.1Kei>
Former Common nameFbxw7b KO, B6-Fbxw7b KO
H-2 Haplotype
ES Cell lineE14 [129P2/OlaHsd]
Background strain
Strain developmentDeveloped by Keiichi Nakayama, Medical Institute of Bioregulation, Kyushu University. E14 ES cells were used. The mutant mice were crossed to C57BL/6J (N6 generations).
Strain descriptionFbxw7 bete isoform knockout mice (delta E1 beta type).
Colony maintenanceHomozygote x Homozygote [or Crossing to C57BL/6JJcl]
ReferencesCancer Sci., 102, 749-755 (2011). 21205095

Health Report

Examination Date / Room / RackNo Data


Gene info
Gene symbolGene nameChr.Allele symbolAllele namePromoter
Fbxw7F-box and WD-40 domain protein 73Fbxw7<tm2.1Kei>targeted mutation 2.1, Kei-ichi Nakayama

Gene symbolGene nameChr.Allele symbolAllele namePromoter
loxPphage P1 loxP3loxP


Donor DNABacteriophage P1 LoxP sequence
Research applicationCell Biology Research
Cre/loxP system
Specific Term and ConditionsPrior to requesting the BIOLOGICAL RESOURCE, the RECIPIENT must obtain approval from the DEPOSITOR using the Approval Form. The RECIPIENT agrees to use this BIOLOGICAL RESOURCE as a collaboration with the DEPOSITOR.
DepositorKeiichi Nakayama (Kyushu University)
Strain Statusan icon for Frozen embryosFrozen embryos
Strain AvailabilityRecovery and QC required prior to distribution
Additional Info.Lab HP

BRC mice in Publications

No Data