RBRC06390

Information1

Image
BRC No.RBRC06390
TypeTargeted MutationCartagena
SpeciesMus musculus
Strain nameB6;129P2-Fbxl5<tm2.1Kei>
Former Common nameFbxl5 cKO, B6-Fbxl5 floxed
H-2 Haplotype
ES Cell lineE14 [129P2/OlaHsd]
Background strain
Appearance
Strain developmentDeveloped by Keiichi Nakayama, Medical Institute of Bioregulation, Kyushu University. E14 ES cells were used. The mutant mice were crossed to C57BL/6J (N7 generations).
Strain descriptionFbx15 gene floxed mice (Flox type). Exons 4 and 5 were flanked by loxP sites.
Colony maintenanceHeterozygote x Wild-type [or Crossing to C57BL/6JJcl]
ReferencesCell Metabolism, 14, 339-351 (2011). 21907140

Health Report

Examination Date / Room / Rack2018/04/02Room:3-6Rack:B
2018/02/05Room:3-6Rack:B
2017/12/04Room:3-6Rack:B
2017/10/02Room:3-6Rack:B
2017/08/21Room:3-6Rack:B
2017/06/05Room:3-6Rack:B
2017/04/03Room:3-6Rack:B
2017/02/06Room:3-6Rack:B

Gene

Gene info
Gene symbolGene nameChr.Allele symbolAllele namePromoter
Fbxl5F-box and leucine-rich repeat protein 55Fbxl5<tm2.1Kei>targeted mutation 2.1, Keiichi I Nakayama

Gene symbolGene nameChr.Allele symbolAllele namePromoter
loxPphage P1 loxP5loxP

Gene symbolGene nameChr.Allele symbolAllele namePromoter
loxPphage P1 loxP5loxP

Information2

Donor DNABacteriophage P1 loxP sites, mouse Fbxl5 genomic DNA
Research applicationCre/loxP system
Metabolism Research
Specific Term and ConditionsPrior to requesting the BIOLOGICAL RESOURCE, the RECIPIENT must obtain approval from the DEPOSITOR using the Approval Form. The RECIPIENT agrees to use this BIOLOGICAL RESOURCE as a collaboration with the DEPOSITOR.
DepositorKeiichi Nakayama (Kyushu University)
Strain Statusan icon for Frozen embryosFrozen embryos
an icon for Frozen spermFrozen sperm
Strain AvailabilityRecovered litters from cryopreserved embryos (2 to 4 months)
Cryopreserved sperm (within 1 month)
Additional Info.Lab HP
Genotyping protocol -PCR-

BRC mice in Publications

No Data