RBRC06330

Information1

Image
BRC No.RBRC06330
TypeTransgeneCartagena
SpeciesMus musculus
Strain nameC57BL/6-Tg(Ly6a-KDM1A*v2)6Fscr
Former Common nameLSD1 Tg#6, B6-Ly6A-KDM1A/v2 Tg#6
H-2 Haplotype
ES Cell line
Background strain
Appearance
Strain developmentDeveloped by Taeko Wada, Center for Molecular Medicine, Jichi Medical University in 2012. The transgene was injected into the pronuclei of C57BL/6 fertilized eggs. Line 3 (RBRC06329), Line 6 (R BRC06330).
Strain descriptionLy6A-KDM1A transgenic mice. These mice express the human KDM1A (LSD1) (transcript variant 2) under the control of the mouse Ly6A promoter. Tg mice show no obvious abnormality. Under investigation (details unknown).
Colony maintenanceCarrier x Noncarrier [C57BL/6JJmsSlc]
ReferencesNat Med. 11, 605-611, (2012). 22406747
Cancer Cell. 21(4):473-487, U, (2012). 22464800

Health Report

Examination Date / Room / Rack2014/09/16Room:4-ARack:E

Gene

Gene info
Gene symbolGene nameChr.Allele symbolAllele namePromoter
KDM1Alysine (K)-specific demethylase 1A (human)UNKDM1Amouse Sca-1(Ly6A) promoter

Gene symbolGene nameChr.Allele symbolAllele namePromoter
neoneomycin resistance gene (E. coli)UN

Gene symbolGene nameChr.Allele symbolAllele namePromoter
SV40 polyA signalUN

Information2

Donor DNAE. coli Neomycin resistance gene, Human LSD1(KDM1A)gene cDNA, mouse Sca-1(Ly6A) promoter, SV40 PolyA signal
Research applicationCancer Research
Specific Term and ConditionsPrior to requesting the BIOLOGICAL RESOURCE, the RECIPIENT must obtain approval from the DEPOSITOR using the Approval Form. In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested. 後日指定。(will be announced).
DepositorYusuke Furukawa (Jichi Medical University)
Strain Statusan icon for Frozen spermFrozen sperm
Strain AvailabilityRecovered litters from cryopreserved sperm (2 to 4 months)
Cryopreserved sperm (within 1 month)
Additional Info.Genotyping protocol -PCR-

BRC mice in Publications

No Data