RBRC06308

Information1

Image
BRC No.RBRC06308
TypeTargeted Mutation CongenicCartagena
SpeciesMus musculus
Strain nameB6.129-(D1Mit501-Fcgr2b) Fcgr2b<tm1Ttk>/Hros
Former Common nameKO2, B6-D1Mit501-Fcgr2b/Fcgr2b KO
H-2 Haplotype
ES Cell line
Background strain
Appearance
Strain developmentDeveloped by Sachiko Hirose, Juntendo University School of Medicine.
Strain descriptionFcgr2b gene knockout mice. This strain carries a chromosomal region of D1Mit501 to Fcgr2b derived from 129 ES cells and Fcgr2b knockout allele. Homozygous mutant mice show no obvious abnormality.
Colony maintenanceD1Mit501-Fcgr2b: Homozygote x Homozygote; Fcgr2b: Homozygote x Homozygote [or Crossing to C57BL/6NCrlCrlj]
ReferencesNature, 379, 346-349 (1996). 8552190
Arthritis Rheum., 63, 2930-2938 (2011). 21953083

Health Report

Examination Date / Room / Rack2018/10/15Room:3-BRack:E
2018/08/20Room:3-BRack:E
2018/06/18Room:3-BRack:E
2018/04/16Room:3-BRack:E
2018/02/19Room:3-BRack:E
2017/12/18Room:3-BRack:E
2017/10/16Room:3-BRack:E
2017/08/21Room:3-BRack:E

Gene

Gene info
Gene symbolGene nameChr.Allele symbolAllele namePromoter
Fcgr2bFc receptor, IgG, low affinity IIb1Fcgr2b<tm1Ttk>targeted mutation 1, Toshiyuki Takai

Gene symbolGene nameChr.Allele symbolAllele namePromoter
neoneomycin resistance gene (E. coli)1

Information2

Donor DNAmouse Fcgr2b genomic DNA, E. coli Neomycin resistance gene
Research applicationImmunology and Inflammation Research
Specific Term and ConditionsIn publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested. Arthritis Rheum., 63, 2930-2938 (2011).
DepositorSachiko Hirose (Juntendo University)
Strain Statusan icon for Frozen embryosFrozen embryos
an icon for Frozen spermFrozen sperm
Strain AvailabilityCryopreserved sperm (within 1 month)
Cryopreserved embryos (within 1 month)
Live mouse (3 to 6 months)
Additional Info.Genotyping protocol -PCR-

BRC mice in Publications

No Data