RBRC06296

Information1

Image
BRC No.RBRC06296
TypeTargeted MutationCartagena
SpeciesMus musculus
Strain nameCAJcl.Cg-Aicda<tm2.1Hon>
Former Common nameBALBcAJcl-AID G23S, BALBcA-AID/G23S KI
H-2 Haplotype
ES Cell lineBruce 4 [B6.Cg-Thy1<a>]
Background strain
Appearance
Strain developmentDeveloped by Reiko Shinkura, Nagahama Institute of Bio-Science and Technology, and Tasuku Honjo, Graduate School of Medicine, Kyoto University. Bruce 4 ES cells were used. The mutant mice were backcrossed to BALB/cAJcl.
Strain descriptionAicda G23S mutant knock-in mice. BALB/cAJcl background. For the details, please contact the developer (Dr. Reiko Shinkura, Nagahama Institute of Bio-Science and Technology).
Colony maintenanceHomozygote x Homozygote [or Crossing to BALB/cAJcl]
ReferencesNat. Immunol., 5, 707-712 (2004). 15195091
Nat. Immunol., 12, 264-270 (2011). 21258321

Health Report

Examination Date / Room / Rack2015/02/16Room:3-ARack:F
2014/12/15Room:3-ARack:F
2014/10/20Room:3-ARack:F
2014/08/18Room:3-ARack:F

Gene

Gene info
Gene symbolGene nameChr.Allele symbolAllele namePromoter
Aicdaactivation-induced cytidine deaminase6Aicda<tm2.1Hon>targeted mutation 2.1, Tasuku Honjo

Gene symbolGene nameChr.Allele symbolAllele namePromoter
loxPphage P1 loxP6loxP

Information2

Donor DNAPhage P1 loxP site, mouse Aicda (G23S) genomic DNA
Research applicationCre/loxP system
Immunology and Inflammation Research
Specific Term and Conditions1) The RECIPIENT shall use the BIOLOGICAL RESOURCE only for academic research for the purpose of publishing the research results.
2) In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, an acknowledgment to the DEPOSITOR and a citation of the following literature(s) designated by the DEPOSITOR are requested. Nat. Immunol., 12, 264-270 (2011).
3) RECIPIENT shall notify the PROVIDER upon filing a patent application claiming modification of the BIOLOGICAL RESOURCE or method(s) of manufacture or use(s) of the BIOLOGICAL RESOURCE.
DepositorTasuku Honjo (Kyoto University)
Strain Statusan icon for Frozen spermFrozen sperm
Strain AvailabilityRecovered litters from cryopreserved sperm (2 to 4 months)
Cryopreserved sperm (within 1 month)
Additional Info.Honjo Lab HP

BRC mice in Publications

No Data