RBRC06239

Information1

Image
BRC No.RBRC06239
TypeTargeted MutationCartagena
SpeciesMus musculus
Strain nameC57BL/6-Siglec1<tm1(cre)Mtka>
Former Common nameCD169-Cre, B6-Siglec1/Cre KI
H-2 Haplotype
ES Cell lineD3 [129S2/SvPas]
Background strainC57BL/6JJcl
Appearance
Strain developmentDeveloped by Dr. Masato Tanaka, Tokyo University of Pharmacy and Life Sciences, School of Life Science. B6JN/1 ES cells were used. C57BL/6 background.
Strain descriptionCD169 (Siglec1) cre knock-in mice. iCre recombinase is expressed from CD169 locus.
Colony maintenanceHeterozygote x Wild-type [C57BL/6JJcl]
ReferencesNat. Commun., 6:7802 (2015). 26193821
J. Am. Soc. Nephrol., 26, 896-906 (2015). 25266072
Genesis, 32(1):19-26 (2002). 11835670

Health Report

Examination Date / Room / Rack2020/06/15Room:3-2Rack:C
2020/06/08Room:3-2Rack:C
2020/04/06Room:3-2Rack:C
2020/02/03Room:3-2Rack:C
2019/12/02Room:3-2Rack:C
2019/11/14Room:3-2Rack:C
2019/11/14Room:3-2Rack:C
2019/10/16Room:3-2Rack:C

Gene

Gene info
Gene symbolGene nameChr.Allele symbolAllele namePromoter
Siglec1sialic acid binding Ig-like lectin 1, sialoadhesin2Siglec1<tm1(cre)Mtka>targeted mutation 1, Masato Tanaka

Gene symbolGene nameChr.Allele symbolAllele namePromoter
iCrephage P1 codon improved Cre (iCre)2iCre

Gene symbolGene nameChr.Allele symbolAllele namePromoter
neoneomycin resistance gene (E. coli)2mouse phosphoglycerate kinase promoter (PGK promoter)

Gene symbolGene nameChr.Allele symbolAllele namePromoter
polyoma virus polyA2

Information2

Donor DNAPhage P1 improved Cre recombinase, mouse phosphoglycerate kinase promoter (PGK promoter), E. coli neo, polyoma virus polyA, mouse Siglec1 genomic DNA
Research applicationCre/loxP system
Immunology and Inflammation Research
Specific Term and ConditionsThe RECIPIENT of BIOLOGICAL RESOURCE shall obtain a prior written consent on use of it from the DEPOSITOR/DEVELOPER. In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested. J. Am. Soc. Nephrol., 26, 896-906 (2015).In publishing the research results to be obtained by use of the BIOLOGICAL RESOURCE, an acknowledgment to the DEPOSITOR is requested. The RECIPIENT agrees to use the BIOLOGICAL RESOURCE as a collaboration with the DEPOSITOR/DEVELOPER, and then include them as co-authors in any publications resulted by the use of the BIOLOGICAL RESOURCE.
DepositorMasato Tanaka (Tokyo University of Pharmacy and Life Sciences)
Strain Statusan icon for Live miceLive mice
an icon for Frozen embryosFrozen embryos
an icon for Frozen spermFrozen sperm
Strain AvailabilityCryopreserved sperm (within 1 month)
Live mouse (1 to 3 months)
Additional Info.Genotyping protocol -PCR-

BRC mice in Publications

No Data