RBRC06229

Information1

Image
BRC No.RBRC06229
TypeTargeted MutationCartagena
SpeciesMus musculus
Strain nameC.B6-Bcl11b<tm2.1Jpk>
Former Common nameBALB-Bcl11b floxed
H-2 Haplotype
ES Cell lineRENKA [C57BL/6NCrlCrlj]
Background strainBALB/cAJcl
Appearance
Strain developmentDeveloped by Ryo Kominami, Graduate School of Medical and Dental Science and Kenji Sakimura, Brain Research Institute, Niigata University. RENKA ES cells derived from C57BL/6NCrlCrlj were used for the generation of floxed mice. Neo cassette was removed by crossing with B6-CAG-FLPe mice (RBRC01824). C57BL/6 background (RBRC06226), BALB/c background (RBRC06229).
Strain descriptionBcl11b floxed mice. Exon 2 was flanked by loxP sites. C57BL/6 background (RBRC06226), BALB/c background (RBRC06229).
Colony maintenanceHomozygote x Homozygote [or Crossing to BALB/cAJcl]
ReferencesCancer Sci., 104. 1009-1016 (2013). 23663453

Health Report

Examination Date / Room / RackNo Data

Gene

Gene info
Gene symbolGene nameChr.Allele symbolAllele namePromoter
Bcl11bB cell leukemia/lymphoma 11B12Bcl11b<tm2.1Jpk>targeted mutation 2.1, Japan Kominami

Gene symbolGene nameChr.Allele symbolAllele namePromoter
Frtyeast FRT (flippase recombination target) site12Frt

Gene symbolGene nameChr.Allele symbolAllele namePromoter
loxPphage P1 loxP12loxP

Information2

Donor DNAP1 phage loxP, Saccharomyces cerevisiae FRT, mouse Bcl11b genomic DNA
Research applicationCancer Research
Cre/loxP system
FLP/frt system
Specific Term and ConditionsPrior to requesting the BIOLOGICAL RESOURCE, the RECIPIENT must obtain approval from the DEPOSITOR using the Approval Form.
DepositorRyo Kominami (Niigata University)
Strain Statusan icon for Frozen embryosFrozen embryos
Strain AvailabilityRecovery and QC required prior to distribution
Additional Info.

BRC mice in Publications

No Data