RBRC06225

Information1

Image
BRC No.RBRC06225
TypeTargeted MutationCartagena
SpeciesMus musculus
Strain nameB6;129-Slc39a7<tm1>
Former Common nameZIP7 KO, B6-Slc39a7 floxed
H-2 Haplotype
ES Cell lineR1 [(129X1/SvJ x 129S1/Sv)F1-Kitl<+>]
Background strain
Appearance
Strain developmentDeveloped by Toshiyuki Fukuda, RIKEN Center for Allergy and Immunology in 2013. R1 ES cells derived from (129X1/SvJ x 129S1/Sv)F1-Kitl<+> were used for the generation of floxed mice. The mutant mice were crossed to C57BL/6J over 9 times.
Strain descriptionZip7 (Slc39a7) gene floxed mice. Exons 5 and 6 were flanked by loxP sites.
Colony maintenanceHomozygote x Homozygote [or Crossing to C57BL/6JJcl]
ReferencesPLOS Genetics 12(10): e1006349 (2016). 27736879
J. Invest Dermatol., 137(8), 1682-1691(2017). 28545780

Health Report

Examination Date / Room / RackNo Data

Gene

Gene info
Gene symbolGene nameChr.Allele symbolAllele namePromoter
Slc39a7solute carrier family 39 (zinc transporter), member 717Slc39a7<tm1>targeted mutation 1

Gene symbolGene nameChr.Allele symbolAllele namePromoter
loxPphage P1 loxP17loxP

Gene symbolGene nameChr.Allele symbolAllele namePromoter
loxPphage P1 loxP17loxP

Information2

Donor DNAEnterobacteria phage P1 loxP, mouse Slc39a13 genomic DNA
Research applicationDevelopmental Biology Research
Specific Term and ConditionsPrior to requesting the BIOLOGICAL RESOURCE, the RECIPIENT must obtain approval from the DEPOSITOR using the Approval Form. In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested. PLOS Genetics 12(10): e1006349, (2016).
DepositorDrs. Shigeo Koyasu and Toshiyuki Fukada (RIKEN)
Strain Statusan icon for Frozen embryosFrozen embryos
Strain AvailabilityRecovery and QC required prior to distribution
Additional Info.

BRC mice in Publications

No Data