RBRC06221

Information1

Image
BRC No.RBRC06221
TypeTargeted MutationCartagena
SpeciesMus musculus
Strain nameB6;129-Slc39a10<tm1.1Tfk>
Former Common nameZIP10 floxed, B6-Slc39a10 floxed
H-2 Haplotype
ES Cell lineR1 [(129X1/SvJ x 129S1/Sv)F1-Kitl<+>]
Background strain
Appearance
Strain developmentDeveloped by Toshiyuki Fukuda, RIKEN Center for Allergy and Immunology in 2013. R1 ES cells derived from (129X1/SvJ x 129S1/Sv)F1-Kitl<+> were used for the generation of floxed mice. The mutant mice were crossed to C57BL/6J over 9 times.
Strain descriptionZip10 (Slc39a10) gene floxed mice. Exons from 6 to 8 were flanked by loxP sites.
Colony maintenanceHomozygote x Homozygote [or Crossing to C57BL/6JJcl]
ReferencesProc. Natl. Acad. Sci. USA, 114:12243-12248 (2017). 29078349
Proc. Natl. Acad. Sci. USA, 111:11780-11785 (2014). 25074913
Proc. Natl. Acad. Sci. USA, 111:11786-11791 (2014). 25074919

Health Report

Examination Date / Room / Rack2017/04/03Room:3-6Rack:B
2017/02/06Room:3-6Rack:B
2016/12/05Room:3-6Rack:B
2016/10/03Room:3-6Rack:B
2016/08/08Room:3-6Rack:B
2016/06/06Room:3-6Rack:B
2016/04/04Room:3-6Rack:B
2016/02/01Room:3-6Rack:B

Gene

Gene info
Gene symbolGene nameChr.Allele symbolAllele namePromoter
Slc39a10solute carrier family 39 (zinc transporter), member 101Slc39a10<tm1.1Tfk>targeted mutation 1.1, Toshiyuki Fukada

Gene symbolGene nameChr.Allele symbolAllele namePromoter
loxPphage P1 loxP1loxP

Gene symbolGene nameChr.Allele symbolAllele namePromoter
loxPphage P1 loxP1loxP

Information2

Donor DNAEnterobacteria phage P1 loxP sites, mouse Slc39a10 genomic DNA
Research applicationCre/loxP system
Developmental Biology Research
Specific Term and ConditionsPrior to requesting the BIOLOGICAL RESOURCE, the RECIPIENT must obtain approval from the DEPOSITOR using the Approval Form. In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested. Proc Natl Acad Sci U S A. ;114(46):12243-12248 (2017). Proc. Natl. Acad. Sci. USA,, 111, 11786-11791, 2014. Proc. Natl. Acad. Sci. USA,, 111, 11780-11785, 2014.
DepositorDrs. Shigeo Koyasu and Toshiyuki Fukada (RIKEN)
Strain Statusan icon for Frozen spermFrozen sperm
Strain AvailabilityRecovered litters from cryopreserved sperm (2 to 4 months)
Cryopreserved sperm (within 1 month)
Additional Info.Genotyping protocol -PCR-

BRC mice in Publications

No Data