RBRC06192

Information1

Image
BRC No.RBRC06192
TypeTargeted MutationCartagena
SpeciesMus musculus
Strain nameB6.129-Trib3<tm1Nah>
Former Common nameNudin1-KO, B6-Trib3 KO
H-2 Haplotype
ES Cell line
Background strainC57BL/6JJcl
Appearance
Strain developmentDeveloped by Naohiro Hashimoto, National Center for Geriatrics and Gerontology in 2004. The mutant mice were backcrossed to C57BL/6.
Strain descriptionNudin1 (Trib3) gene knockout mice. Homozygous mutant mice show no obvious abnormality.
Colony maintenanceHomozygote x Homozygote [or Crossing to C57BL/6JJcl]
ReferencesJ. Neurosci. Res., 85(16):3586-97 (2007). 17722065
Biochem. Biophys. Res. Commun., 279, 62-68 (2000). 11112418

Health Report

Examination Date / Room / Rack2015/07/06Room:2-3Rack:A
2015/05/11Room:2-3Rack:A
2015/03/09Room:2-3Rack:A
2015/01/13Room:2-3Rack:A
2014/11/10Room:2-3Rack:A
2014/09/08Room:2-検Rack:N
2014/07/07Room:2-検Rack:N
2014/05/12Room:2-検Rack:N

Gene

Gene info
Gene symbolGene nameChr.Allele symbolAllele namePromoter
Trib3ribbles homolog 3 (Drosophila)2Trib3<tm1Nah>targeted mutation 1, Naohiro Hashimoto

Gene symbolGene nameChr.Allele symbolAllele namePromoter
neoneomycin resistance gene (Klebsiella pneumoniae)2mouse phosphoglycerate kinase promoter (PGK promoter)

Information2

Donor DNAmouse phosphoglycerate kinase promoter (PGK promoter), Klebsiella pneumoniae neomycin resistance gene, mouse Trib3 genomic DNA
Research applicationDiabetes and Obesity Research
Specific Term and ConditionsNo specific terms and conditions. (The DEPOSITOR waives its own rights under any patents, intellectual property, or other proprietary rights with respect to the results to be obtained by use of the BIOLOGICAL RESOURCE.)
DepositorNaohiro Hashimoto (National Center for Geriatrics and Gerontology)
Strain Statusan icon for Frozen embryosFrozen embryos
an icon for Frozen spermFrozen sperm
Strain AvailabilityRecovered litters from cryopreserved sperm (2 to 4 months)
Cryopreserved sperm (within 1 month)
Additional Info.Genotyping protocol -PCR-

BRC mice in Publications

No Data