BRC No.RBRC06155
SpeciesMus musculus
Strain nameC.Cg-Tg(CAG-Cre)CZ-M02Osb
Former Common nameCAG-Cre, BALB-CAGCre Tg#2
H-2 Haplotype
ES Cell line
Background strainBALB/cAJcl
Strain developmentDeveloped by Shuhei Sakakibara and Teruhito Yasui, Research Institute for Microbial Diseases, Osaka University. Generated by backcrossing to BALB/cAJcl from B6.Cg-Tg(CAG-Cre)CZ-M02Osb (RBRC01828) over 11 times.
Strain descriptionThese transgenic mice express Cre recombinase gene under the control of CAG promoter. This strain can be used to make an inducible knock-out by crossing with the other genetically-engineered mice that have a loxP site-flanked sequence of interest. The recombination occurs in all over the body. BALB/c background.
Colony maintenanceCarrier x Noncarrier [BALB/cAJcl]
ReferencesBiochem. Biophys. Res. Commun., 321, 275-279 (2004). 15358172

Health Report

Examination Date / Room / Rack2015/09/28Room:4-BRack:F


Gene info
Gene symbolGene nameChr.Allele symbolAllele namePromoter
crePhage P1 Cre recombinaseUNcreCAG promoter (CMV-IE enhancer, chicken beta-actin promoter, rabbit beta-globin genomic DNA)


Donor DNACAG promoter (CMV-IE enhancer, chicken beta-actin promoter, rabbit beta-globin genomic DNA) Phage P1 Cre recombinase
Research applicationCre/loxP system
Specific Term and ConditionsIn publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested. Biochem. Biophys. Res. Commun., 321, 275-279 (2004).RECIPIENT which wants to use the BIOLOGICAL RESOURCE for the purpose other than education or not-for-profit research is required to enter into a Material Transfer Agreement with Osaka University. (http://www.uic.osaka-u.ac.jp/en/index.html)
DepositorTeruhito Yasui (Osaka University)
Strain Statusan icon for Frozen spermFrozen sperm
Strain AvailabilityRecovered litters from cryopreserved sperm (2 to 4 months)
Cryopreserved sperm (within 1 month)
Additional Info.Genotyping protocol -PCR-

BRC mice in Publications

K Joh, F Matsuhisa, S Kitajima, K Nishioka, K Higashimoto, H Yatsuki, T Kono, H Koseki and H Soejima.
Growing oocyte specific transcription-dependent de novo DNA methylation at the imprinted Zrsr1-DMR.
Epigenetics Chromatin (2018) 29875017