Strain Data Sheet



BRC No.RBRC06137
SpeciesMus musculus
Strain nameICR.Cg-Tg(TP1-venus)/YsaRbrc
Former Common nameICR-TP1-venus, TP1-venus (ICR)
H-2 Haplotype
ES Cell line
Background strain
Strain developmentDeveloped by Yumiko Saga, National Institute of Genetics. ICR mixed background.
Strain descriptionTP1-venus transgenic mice. Notch reporter mice, in which venus expression was induced upon activation of Notch signaling via RBP-jk-binding sequence.
Colony maintenanceCarrier x Noncarrier [or Crossing to Jcl:MCH(ICR)]
ReferencesDevelopment, 138, 55-64 (2011). 21098559
Dev Biol., 286, 311-325 (2005). 16153632

Health Report

Examination Date / Room / Rack


Gene info
Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter
VenusYellow Fluorescent Protein (Aequorea victoria)UNVenus12 tandem RBP-J binding site, rBG minimum promoter


Donor DNA12 tandem RBP-J binding site, rBG minimum promoter, Jellyfish venus cDNA, SV40 polyA, pTI(L), pTI(R), HS4 insulator corex2
Research applicationDevelopmental Biology Research
Fluorescent Proteins/lacZ System
Specific Term and ConditionsIn publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested. Development, 138, 55-64 (2011). Dev Biol., 286, 311-325 (2005).In publishing the research results to be obtained by use of the BIOLOGICAL RESOURCE, an acknowledgment to the DEPOSITOR is requested. The RECIPIENT agrees to use this BIOLOGICAL RESOURCE as a collaboration with the DEPOSITOR/DEVELOPER. The RECIPIENT shall obtain a prior written consent on use of it from the DEPOSITOR.
DepositorYumiko Saga (National Institute of Genetics)
Strain Statusan icon for Frozen spermFrozen sperm
Strain AvailabilityRecovered litters from cryopreserved sperm (2 to 4 months)
Cryopreserved sperm (within 1 month)
Additional Info.Necessary documents for ordering:
  1. Order form (Japanese / English)
  2. Category I MTA: MTA for distribution with RIKEN BRC (Japanese / English)
  3. The RECIPIENT of BIOLOGICAL RESOURCE must obtain a prior written consent on use of it from the DEVELOPER of the Venus using Approval form (Form V (English)) (Lab Contact: Laboratory for Cell Function Dynamics, RIKEN CBS:
  4. Acceptance of responsibility for living modified organism (Japanese / English)
Saga Lab HP
Genotyping protocol -PCR-

BRC mice in Publications

Cui S, Li L, Yu RT, Downes M, Evans RM, Hulin JA, Makarenkova HP, Meech R.
β-Catenin is essential for differentiation of primary myoblasts via cooperation with MyoD and α-catenin.
Development 146(6) (2019) 30683662

Hulin JA, Nguyen TD, Cui S, Marri S, Yu RT, Downes M, Evans RM, Makarenkova H, Meech R.
Barx2 and Pax7 Regulate Axin2 Expression in Myoblasts by Interaction with β-Catenin and Chromatin Remodelling.
Stem Cells 34(8) 2169-82(2016) 27144473