BRC No.RBRC06136
TypeTargeted MutationCartagena
SpeciesMus musculus
Strain nameB6.Cg-Fad24<tm1Maim>/53B
Former Common nameFad24 hetero #53B, B6-Fad24 KO#53B
H-2 Haplotype
ES Cell lineEGR-G01 [129S2 x C57BL/6NCr-Tg(CAG/Acr-EGFP)]
Background strain
Strain developmentDeveloped by Graduate School of Pharmaceutical Sciences, Nagoya City University and Genome Information Research Center, Osaka University in 2010. EGR-G01 ES cells were used. The mutant mice were crossed to C57BL/6 over 8 times.
Strain descriptionFad24 (Noc3l) gene knockout mice. Exons 6-8 and a part of 9 were replaced with a neo cassette. Homozygous mutant mice are embryonic lethal.
Colony maintenanceHeterozygote x Wild-type [C57BL/6J(Crlj)]
ReferencesJ. Biol. Chem., 283, 2265-2274 (2008). 18029353
Biol. Pharm. Bull., 32, 1656-1664 (2008). 19801824
Biochem. Biophys. Res. Commun., 438, 301-305 (2013). 23886952
Biol. Pharm. Bull., 31, 1092-1095 (2008). 18520036
J. Cell Sci., 117, 6217-6226 (2004). 15564382
Biochem. Biophys. Res. Commun., 369, 464-470 (2008). 18284919

Health Report

Examination Date / Room / RackNo Data


Gene info
Gene symbolGene nameChr.Allele symbolAllele namePromoter
Noc3lnucleolar complex associated 3 homolog (S. cerevisiae)19Noc3l<tm1Maim>targeted mutation 1, Masayoshi Imagawa

Gene symbolGene nameChr.Allele symbolAllele namePromoter
neoneomycin resistance gene (E. coli)19mouse phosphoglycerate kinase promoter (PGK promoter)


Donor DNAE. coli Neomysin resistance gene, mouse PGK promoter, HSV-tk, mouse PGK polyA
Research applicationDevelopmental Biology Research
Specific Term and ConditionsIn publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested. Biochem. Biophys. Res. Commun., 438, 301-305 (2013).In publishing the research results to be obtained by use of the BIOLOGICAL RESOURCE, an acknowledgment to the DEPOSITOR is requested. Prior to requesting the BIOLOGICAL RESOURCE, the RECIPIENT must obtain approval from Dr.Makoto Nishizuka (nishizuka@hirosaki-u.ac.jp) using the Approval Form. For use of the BIOLOGICAL RESOURCE by a for-profit institution, the RECIPIENT must reach agreement on terms and conditions of use of it with DEPOSITOR and must obtain a prior written consent from the DEPOSITOR. The RECIPIENT must contact the DEPOSITOR in the case of application for any patents or commercial use based on the results from the use of the BIOLOGICAL RESOURCE.
DepositorMasayoshi Imagawa (Nagoya City University)
Strain Statusan icon for Frozen spermFrozen sperm
Strain AvailabilityRecovered litters from cryopreserved sperm (2 to 4 months)
Cryopreserved sperm (within 1 month)
Additional Info.

BRC mice in Publications

No Data