RBRC06029

Information1

Image
BRC No.RBRC06029
TypeTargeted MutationCartagena
SpeciesMus musculus
Strain nameB6;129S2-Kpna4<tm1Yyo>
Former Common nameImpa3-
H-2 Haplotype
ES Cell line
Background strain
Appearance
Strain developmentDeveloped by Masahiro Nagai and Yoshihiro Yoneda, Graduate School of Frontier Biosciences, Osaka University.
Strain descriptionKpna4 (IPOA3, Impoirtin alpha 3) gene knockout mice. Exons 2 to 5 were replaced with a neo cassette. Homozygous mutant mice show no obvious abnormality.
Colony maintenanceHomozygote x Homozygote [or Crossing to C57BL/6JJcl]
References

Health Report

Examination Date / Room / RackNo Data

Gene

Gene info
Gene symbolGene nameChr.Allele symbolAllele namePromoter
Kpna4karyopherin (importin) alpha 43Kpna4<tm1Yyo>targeted mutation 1, Yoshihiro Yoneda

Gene symbolGene nameChr.Allele symbolAllele namePromoter
loxPphage P1 loxP3loxP

Gene symbolGene nameChr.Allele symbolAllele namePromoter
loxPphage P1 loxP3loxP

Gene symbolGene nameChr.Allele symbolAllele namePromoter
neoneomycin resistance gene (E. coli)3mouse phosphoglycerate kinase promoter (PGK promoter)

Information2

Donor DNAE. coli Neomycin resistance gene, Mouse Phosphoglycerate kinase promoter (PGK promoter), Bacteriophage P1 locus of X-over P1 (loxP), Mouse Kpna4 genomic DNA
Research applicationCell Biology Research
Cre/loxP system
Immunology and Inflammation Research
Specific Term and ConditionsPrior to requesting the BIOLOGICAL RESOURCE, the RECIPIENT must obtain approval from the DEPOSITOR using the Approval Form. In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, the RECIPIENT must contact the DEPOSITOR and notify him the research content. If the DEPOSITOR judges that the research should be a collaborative work, then the RECIPIENT must include the DEPOSITOR/DEVELOPER as co-authors.
DepositorMasahiro Oka (National Institutes of Biomedical Innovation, Health and Nutrition)
Strain Statusan icon for Frozen embryosFrozen embryos
Strain AvailabilityRecovery and QC required prior to distribution
Additional Info.

BRC mice in Publications

No Data