RBRC06023

Information1

Image
BRC No.RBRC06023
TypeTransgene CongenicCartagena
SpeciesMus musculus
Strain nameICR.Cg-Tg(Sox2-luc2/Sox2)1Imayo
Former Common nameLuc2-Sox2 fusion BAC ; Sox2-luc2/Sox2 Tg#1
H-2 Haplotype
ES Cell line
Background strain
Appearance
Strain developmentDeveloped by Itaru Imayoshi and Ryoichiro Kageyama, Institute for Virus Research, Kyoto University in 2011. The transgene was injected into the pronuclei of ICR fertilized eggs.
Strain descriptionSox2 BAC transgenic mice, in which luc2-Sox2 fusion protein is expressed.
Colony maintenanceCarrier x Noncarrier [or Crossing to Slc:ICR]
ReferencesScience DOI: 10.1126/science.1242366 24179156

Health Report

Examination Date / Room / Rack2015/11/09Room:2-3Rack:A
2015/09/07Room:2-3Rack:A
2015/07/06Room:2-3Rack:A

Gene

Gene info
Gene symbolGene nameChr.Allele symbolAllele namePromoter
Frtyeast FRT (flippase recombination target) siteUNFrt

Gene symbolGene nameChr.Allele symbolAllele namePromoter
HAhuman influenza virus HA (hemagglutinin) tag sequenceUNHA

Gene symbolGene nameChr.Allele symbolAllele namePromoter
loxPphage P1 loxPUNloxP

Gene symbolGene nameChr.Allele symbolAllele namePromoter
luc2Photinus pyralis LuciferaseUNluc2

Information2

Donor DNAmouse Sox2 genomic DNA (BAC clone RP23-4D1), HA (hemagglutinin) tag sequence, Optimized luciferase cDNA (synthetic), yeast Frt (flippase recombination target) site, Phage P1 loxP site
Research applicationCre/loxP system
FLP/frt system
Specific Term and ConditionsIn publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested. Science DOI: 10.1126/science.1242366In publishing the research results to be obtained by use of the BIOLOGICAL RESOURCE, an acknowledgment to the DEPOSITOR is requested. The availability of the BIOLOGICAL RESOURCE is limited to a RECIPIENT of a not-for profit institution for a not-for-profit research. The RECIPIENT of BIOLOGICAL resource shall obtain a prior written consent on use of it from the DEPOSITOR Dr. Itaru Imayoshi (E-mail: iimayosh@virus.kyoto-u.ac.jp) and Ryoichiro Kageyama (E-mail: rkageyam@virus.kyoto-u.ac.jp ). (No approval form (Form D) is necessary).
DepositorDrs. Ryoichiro Kageyama and Itaru Imayoshi (Kyoto University)
Strain Statusan icon for Frozen spermFrozen sperm
Strain AvailabilityRecovered litters from cryopreserved sperm (2 to 4 months)
Cryopreserved sperm (within 1 month)
Additional Info.

BRC mice in Publications

No Data