RBRC05990

Information1

Image
BRC No.RBRC05990
TypeTransgeneCartagena
SpeciesMus musculus
Strain nameICR;D2-Tg(Hes7-Hes7,venus)1Kag
Former Common nameHes7 Tg ; Hes7-Hes7/venus Tg
H-2 Haplotype
ES Cell line
Background strain
Appearance
Strain developmentDeveloped by Ryoichiro Kageyama, Institute for Virus Research, Kyoto University in 2003. The transgene was injected into the pronuclei of DBA/2 fertilized eggs.
Strain descriptionHes7 transgenic mice Transgene composed of 5.4kb Hes7 promoter-1st exon-1st intron-2nd exon-Hes7 cDNA(ORF of the 1st&2nd exons are deleted)-IRES-Venus-SV40 polyA Hes7 expression is up-regulated and initially oscillates but later becomes sustained.
Colony maintenanceCarrier x Noncarrier [or Crossing to Slc:ICR]
ReferencesDev Cell. 2007 13(2):298-304. 17681139

Health Report

Examination Date / Room / RackNo Data

Gene

Gene info
Gene symbolGene nameChr.Allele symbolAllele namePromoter
Hes7hairy and enhancer of split 7 (Drosophila)UNHes7

Gene symbolGene nameChr.Allele symbolAllele namePromoter
Iresinternal ribosomal entry site (EMCV)UN

Gene symbolGene nameChr.Allele symbolAllele namePromoter
VenusGreen Fluorescent Protein, F46L (Jellyfish)UNVenus

Gene symbolGene nameChr.Allele symbolAllele namePromoter
SV40 polyAUN

Information2

Donor DNAmouse Hes7 promoter, 1st exon, 1st intron and 2nd exon of Hes7 gene, EMCV (Encephalomyocarditis virus) internal ribosomal entry site (IRES), Jellyfish Venus, SV40 polyA
Research application
Specific Term and ConditionsIn publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested. Dev Cell. 2007 13(2):298-304.In publishing the research results to be obtained by use of the BIOLOGICAL RESOURCE, an acknowledgment to the DEPOSITOR is requested. The availability of the BIOLOGICAL RESOURCE is limited to a RECIPIENT of a not-for profit institution for a not-for-profit research. The RECIPIENT of BIOLOGICAL resource shall obtain a prior written consent on use of it from the DEPOSITOR Dr. Ryoichiro Kageyama (E-mail: rkageyam@virus.kyoto-u.ac.jp ). (No approval form (Form D) is necessary).
DepositorDrs. Itaru Imayoshi and Ryoichiro Kageyama (Kyoto University)
Strain Statusan icon for Frozen embryosFrozen embryos
Strain AvailabilityRecovery and QC required prior to distribution
Additional Info.

BRC mice in Publications

No Data