BRC No.RBRC05986
TypeTargeted Mutation CongenicCartagena
SpeciesMus musculus
Strain nameICR.Cg-Neurod4<tm1Kag>
Former Common nameMath3 KO ; Neurod4 KO
H-2 Haplotype
ES Cell lineTT2 [(C57BL/6NCrlj x CBA/JNCrlj)F1]
Background strain
Strain developmentDeveloped by Ryoichiro Kageyama, Institute for Virus Research, Kyoto University in 1999. TT2 ES cells were used. The mutant mice were crossed to ICR.
Strain descriptionMath3 (Neurod4) gene knockout mice. Exon 2 was replaced with a neo cassette.
Colony maintenanceHeterozygote x Wild-type [or Crossing to Slc:ICR]
ReferencesEMBO J. 2000 19(20):5460-72. 11032813

Health Report

Examination Date / Room / RackNo Data


Gene info
Gene symbolGene nameChr.Allele symbolAllele namePromoter
Neurod4neurogenic differentiation 410Neurod4<tm1Kag>targeted mutation 1, Ryoichiro Kageyama

Gene symbolGene nameChr.Allele symbolAllele namePromoter
neoneomycin resistance gene (E. coli)10mouse phosphoglycerate kinase promoter (PGK promoter)


Donor DNAmouse phosphoglycerate kinase promoter (PGK promoter), Neo (E. coli), mouse Math3 genomic DNA
Research application
Specific Term and ConditionsIn publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested. EMBO J. 2000 19(20):5460-72.In publishing the research results to be obtained by use of the BIOLOGICAL RESOURCE, an acknowledgment to the DEPOSITOR is requested. The availability of the BIOLOGICAL RESOURCE is limited to a RECIPIENT of a not-for profit institution for a not-for-profit research. The RECIPIENT of BIOLOGICAL resource shall obtain a prior written consent on use of it from the DEPOSITOR Dr. Ryoichiro Kageyama (E-mail: rkageyam@virus.kyoto-u.ac.jp ). (No approval form (Form D) is necessary).
DepositorDrs. Itaru Imayoshi and Ryoichiro Kageyama (Kyoto University)
Strain Statusan icon for Frozen embryosFrozen embryos
Strain AvailabilityRecovery and QC required prior to distribution
Additional Info.

BRC mice in Publications

No Data