RBRC05978

Information1

Image
BRC No.RBRC05978
TypeTargeted Mutation CongenicCartagena
SpeciesMus musculus
Strain nameB6.Cg-Mybbp1a<tm1Jyan>
Former Common nameMYBBP1A-KO, B6-Mybbp1a KO
H-2 Haplotype
ES Cell lineiTL BA1[(C57BL/6N x 129S6/SvEvTac)F1]
Background strain
Appearance
Strain developmentDeveloped by Jun Yanagisawa, Graduate School of Life and Environmental Sciences. iTL BA1 ES cells were used. The mutant mice were crossed to C57BL/6J mice over 8 times.
Strain descriptionMYBBP1A gene knockout mice. Exons 1 to 9 were removed. Homozygous mutant mice are embryonic lethal.
Colony maintenanceHeterozygote x Wild-type [C57BL/6JJcl]
ReferencesBMC Cancer. 2013 Feb 7;13:65. doi: 10.1186/1471-2407-13-65. 23388179
EMBO J., 30, 1054 - 1066 (2011) . 21297583

Health Report

Examination Date / Room / Rack2015/02/18Room:4-ARack:C
2015/02/16Room:4-ARack:C
2015/01/19Room:4-ARack:C
2014/11/17Room:4-ARack:C
2014/11/12Room:4-ARack:C
2014/11/10Room:4-ARack:C
2014/10/15Room:4-ARack:C
2014/09/16Room:4-ARack:C

Gene

Gene info
Gene symbolGene nameChr.Allele symbolAllele namePromoter
Mybbp1aMYB binding protein (P160) 1a11Mybbp1a<tm1Jyan>targeted mutation 1, Jun Yanagisawa

Gene symbolGene nameChr.Allele symbolAllele namePromoter
Frtyeast FRT (flippase recombination target) site11Frt

Gene symbolGene nameChr.Allele symbolAllele namePromoter
loxPphage P1 loxP11loxP

Information2

Donor DNAPhage P1 LoxP, Saccharomyces cerevisiae FRT, mouse Mybbp1a genomic DNA
Research applicationCre/loxP system
FLP/frt system
Specific Term and ConditionsNo specific terms and conditions. (The DEPOSITOR waives its own rights under any patents, intellectual property, or other proprietary rights with respect to the results to be obtained by use of the BIOLOGICAL RESOURCE.)
DepositorJun Yanagisawa (University of Tsukuba)
Strain Statusan icon for Frozen spermFrozen sperm
Strain AvailabilityRecovered litters from cryopreserved sperm (2 to 4 months)
Cryopreserved sperm (within 1 month)
Additional Info.Genotyping protocol -PCR-

BRC mice in Publications

No Data