BRC No.RBRC05933
TypeTargeted MutationCartagena
SpeciesMus musculus
Strain nameB6.Cg-Igf1<tm1.1Hko>
Former Common nameIGF1 Delta lox/+ (GWAS006), B6-Igf1 KO
H-2 Haplotype
ES Cell line
Background strainC57BL/6JJcl
Strain developmentDeveloped by Haruhiko Koseki, RIKEN Center for Allergy and Immunology. B6JN/1 ES cells derived from C57BL/6 were used for the generation of knockout mice. Exon 2 and neo cassette were removed by crossing with CAG-Cre mice (C57BL/6 background). The mutant mice were crossed to C57BL/6J.
Strain descriptionIGF1 (Igf1) gene knockout mice. Exon 2 was removed.
Colony maintenanceHeterozygote x Wild-type [C57BL/6JJcl]

Health Report

Examination Date / Room / RackNo Data


Gene info
Gene symbolGene nameChr.Allele symbolAllele namePromoter
Igf1insulin-like growth factor 110Igf1<tm1.1Hko>targeted mutation 1.1, Haruhiko Koseki

Gene symbolGene nameChr.Allele symbolAllele namePromoter
loxPphage P1 loxP10loxP


Donor DNAmouse Igf1 genomic DNA, phage P1 loxP, CMV IE enhancer, Chicken Beta-actin promoter, rabbit Beta-globin genomic DNA, phage P1 cre
Research applicationCre/loxP system
Specific Term and ConditionsThe RECIPIENT must contact the DEPOSITOR in the case of application for any patents or commercial use based on the results from the use of the BIOLOGICAL RESOURCE.
DepositorHaruhiko Koseki (RIKEN)
Strain Statusan icon for Frozen embryosFrozen embryos
Strain AvailabilityRecovery and QC required prior to distribution
Additional Info.

BRC mice in Publications

No Data