BRC No.RBRC05853
TypeTargeted MutationCartagena
SpeciesMus musculus
Strain nameB6.Cg-Igh<tm1(AK23)>
Former Common nameAK23 IgH KI, B6-IgH KI
H-2 Haplotype
ES Cell line
Background strain
Strain developmentDeveloped by Dr. Shigeo Koyasu, Keio University School of Medicine.
Strain descriptionThe endogenous DQ53 and JH1-4 elements were replaced by a anti-Dsg3 VDJ (AK23) H chain.
Colony maintenanceHeterozygote x Wild-type [C57BL/6NTac]

Health Report

Examination Date / Room / Rack2013/10/21Room:3-DRack:D


Gene info
Gene symbolGene nameChr.Allele symbolAllele namePromoter
Ighimmunoglobulin heavy chain complex12Igh <tm1(AK23)>targeted mutation 1

Gene symbolGene nameChr.Allele symbolAllele namePromoter
neoneomycin resistance gene (E. coli)12


Donor DNAマウス免疫グロブリンエンハンサーとプロモーター (関連無), マウス 免疫グロブリン重鎖遺伝子 (関連無), 大腸菌トランスポソンTn5由来ネオマイシン耐性遺伝子 (関連無)
Research applicationImmunology and Inflammation Research
Specific Term and ConditionsThe RECIPIENT of BIOLOGICAL RESOURCE must include of the DEVELOPER as a co-author of any paper before the DEVELOPER publishes the original paper describing the BIOLOGICAL RESOURCE. After publication of the original paper, the RECIPIENT of BIOLOGICAL RESOURCE must obtain a prior written consent on use of it from the DEPOSITOR/DEVELOPER. but may not include the DEVELOPER as an author.
DepositorShigeo Koyasu (Keio University)
Strain Statusan icon for Frozen spermFrozen sperm
Strain AvailabilityRecovered litters from cryopreserved sperm (2 to 4 months)
Cryopreserved sperm (within 1 month)
Additional Info.Lab HP

BRC mice in Publications

No Data