RBRC05755

Information1

Image
BRC No.RBRC05755
TypeTargeted MutationCartagena
SpeciesMus musculus
Strain nameC57BL/6-Map3k15<tm1Hijo>
Former Common nameASK3 KO, B6-Map3k15 KO
H-2 Haplotype
ES Cell line
Background strainC57BL/6JJcl
Appearance
Strain developmentDeveloped by Hidenori Ichijo, Graduate School of Pharmaceutical Sciences, The University of Tokyo in 2012. C57BL/6 background.
Strain descriptionMap3k15 gene knockout mice. A part of exon 1 was replaced with a neo cassette.
Colony maintenanceHomozygote (female) x Hemizygote (male) [or Crossing to C57BL/6JJcl] Mutant mice (homozygous females and hemizygous males) are viable and fertile.
References

Health Report

Examination Date / Room / Rack2015/08/03Room:3-6Rack:A
2015/06/10Room:3-6Rack:A
2015/06/01Room:3-6Rack:A
2015/04/06Room:3-6Rack:A
2015/02/02Room:3-6Rack:A
2014/12/01Room:3-6Rack:A
2014/10/06Room:3-6Rack:A
2014/08/04Room:3-6Rack:A

Gene

Gene info
Gene symbolGene nameChr.Allele symbolAllele namePromoter
Map3k15mitogen-activated protein kinase kinase kinase 15XMap3k15 <tm1Hijo>targeted mutation 1, Hidenori Ichijo

Gene symbolGene nameChr.Allele symbolAllele namePromoter
loxPphage P1 loxPXloxP

Gene symbolGene nameChr.Allele symbolAllele namePromoter
loxPphage P1 loxPXloxP

Gene symbolGene nameChr.Allele symbolAllele namePromoter
neoneomycin resistance gene (Klebsiella pneumoniae)X

Information2

Donor DNAKlebsiella pneumoniae Neomycin resistance gene, Mouse MAP3K15 genomic DNA, P1 Phage loxP
Research applicationCre/loxP system
Immunology and Inflammation Research
Specific Term and ConditionsPrior to requesting the BIOLOGICAL RESOURCE, the RECIPIENT must obtain approval from the DEPOSITOR using the Approval Form. For use of the BIOLOGICAL RESOURCE by a for-profit institution, the RECIPIENT must reach agreement on terms and conditions of use of it with DEPOSITOR and must obtain a prior written consent from the DEPOSITOR. RECIPIENT must contact the DEPOSITOR in the case of application for any patents or commercial use with the results from the use of the BIOLOGICAL RESOURCE.
DepositorHidenori Ichijo (The University of Tokyo)
Strain Statusan icon for Frozen embryosFrozen embryos
an icon for Frozen spermFrozen sperm
Strain AvailabilityRecovered litters from cryopreserved embryos (2 to 4 months)
Cryopreserved sperm (within 1 month)
Cryopreserved embryos (within 1 month)
Additional Info.

BRC mice in Publications

No Data