BRC No.RBRC05699
TypeTargeted MutationCartagena
SpeciesMus musculus
Strain nameC57BL/6-S100a4<tm1.1>
Former Common nameCAG Cre s100A4 flox, B6-S100a4 KO
H-2 Haplotype
ES Cell lineRENKA [C57BL/6NCrlCrlj]
Background strainC57BL/6NCrlCrlj
Strain developmentDeveloped by Takaji Matsutani and Norihiro Nishimoto in 2009. RENKA ES cells derived from C57BL/6NCrlCrlj were used. S100A4 knock-out allele (S100a4<tm1.1>) was produced by crossing S100A4 floxed (S100a4<tm1>) and CAG-Cre mice (B6.Cg-Tg(CAG-Cre)CZ-MO2Osb).
Strain descriptionS100A4 gene knockout mice.
Colony maintenanceHeterozygote x Wild-type [C57BL/6NCrlCrlj]

Health Report

Examination Date / Room / RackNo Data


Gene info
Gene symbolGene nameChr.Allele symbolAllele namePromoter
S100a4S100 calcium binding protein A43S100a4 <tm1.1>targeted mutation 1.1

Gene symbolGene nameChr.Allele symbolAllele namePromoter
lox71mutant lox sequence3lox71


Donor DNAマウス (Mus musculus) S100a4, ファージ P1 loxP
Research applicationCancer Research
Cell Biology Research
Cre/loxP system
Immunology and Inflammation Research
Specific Term and ConditionsPrior to requesting the BIOLOGICAL RESOURCE, the RECIPIENT must obtain approval from the DEPOSITOR using the Approval Form. In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested. 後日指定(will be announced)In publishing the research results to be obtained by use of the BIOLOGICAL RESOURCE, an acknowledgment to the DEPOSITOR is requested. For use of the BIOLOGICAL RESOURCE by a for-profit institution, the RECIPIENT must reach agreement on terms and conditions of use of it with DEPOSITOR and must obtain a prior written consent from the DEPOSITOR. The RECIPIENT must contact the DEPOSITOR in the case of application for any patents or commercial use based on the results from the use of the BIOLOGICAL RESOURCE.
DepositorNorihito Nishimoto (Wakayama Medical University)
Strain Statusan icon for Frozen embryosFrozen embryos
Strain AvailabilityRecovery and QC required prior to distribution
Additional Info.

BRC mice in Publications

No Data