Strain Information | |
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Image | |
BRC No. | RBRC05662 |
Type | Targeted Mutation![]() |
Species | Mus musculus |
Strain name | B6.Cg-Pcp4<tm2.1(cre)> |
Former Common name | Pcp4-cre, B6-Pcp4/Cre KI |
H-2 Haplotype | |
ES Cell line | Bruce 4 [B6.Cg-Thy1<a>] |
Background strain | |
Appearance | |
Strain development | Developed by Toshitada Takemori, RIKEN Center for Allergy and Immunology in 2008. Bruce 4 ES cells derived from B6.Cg-Thy1.1 were used. A frt flanked neo cassette was removed by crossing with CAG-FLPe mice#23 (B6). |
Strain description | Pcp4 cre knock-in mice. |
Colony maintenance | Heterozygote x Wild-type [C57BL/6JJcl] |
References |
Health Report | |
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Examination Date / Room / Rack |
Gene | |||||||
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Gene Symbol | Gene Name | Chr. | Allele Symbol | Allele Name | Common Names | Promoter | Diseases Related to This Gene |
Frt | yeast FRT (flippase recombination target) site | 16 | Frt | ||||
GH | Growth hormone polyA (Bovine) | 16 | GH | ||||
Pcp4 MGI:97509 | Purkinje cell protein 4 | 16 | Pcp4 <tm2.1(cre)Mtto> | targeted mutation 2.1, Toshitada Takemori | |||
cre | Phage P1 Cre recombinase | 16 | cre |
Phenotype | |
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Annotation by Mammalian phenotyhpe ontology | |
Detailed phenotype data |
Ordering Information | |
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Donor DNA | phage P1 cre recombinase, yeast FRT site, bovine growth hormone polyA signal, mouse Pcp4 genomic DNA |
Research application | Cre/loxP system FLP/frt system Immunology and Inflammation Research Cre driver |
Specific Term and Conditions | In publishing the research results to be obtained by use of the BIOLOGICAL RESOURCE, an acknowledgment to the DEPOSITOR and Dr. Akiko Ishige is requested. |
Depositor | Toshitada Takemori (RIKEN) |
Strain Status | ![]() ![]() |
Strain Availability | Recovered litters from cryopreserved sperm (2 to 4 months) Cryopreserved sperm (within 1 month) |
Additional Info. | Necessary documents for ordering:
Genotyping protocol -PCR- |
BRC mice in Publications |
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Jamiolkowski RM, Nguyen QA, Farrell JS, McGinn RJ, Hartmann DA, Nirschl JJ, Sanchez MI, Buch VP, Soltesz I. The fasciola cinereum of the hippocampal tail as an interventional target in epilepsy. Nat Med 30(5) 1292-1299(2024) 38632391 |